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Summary of Significant Accounting Policies (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2019	Mar. 31, 2018	Jan. 01, 2019
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Allowance for doubtful accounts receivable	$ 300
Net product sales	34,046	$ 16,696
Operating lease, liability	38,412
Operating lease ROU asset	36,208
ASU 2016-02
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Operating lease, liability			$ 17,600
Operating lease ROU asset	15,000
U.S.
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Net product sales	9,068	0
Ex-U.S.
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Net product sales	$ 24,978	$ 16,696

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For an unclassified balance sheet, a valuation allowance for receivables due a company that are expected to be uncollectible.

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