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Summary of Significant Accounting Policies (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended |
--- | --- | --- | ---
Jun. 30, 2019 | Jun. 30, 2018 | Jun. 30, 2019 | Jun. 30, 2018 | Jan. 01, 2019
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |
Allowance for doubtful accounts receivable | $ 200 |  | $ 200 |  |
Net product sales | 44,130 | $ 21,309 | 78,176 | $ 38,005 |
Operating lease, liability | 38,937 |  | 38,937 |  |
Operating lease ROU asset | 35,052 |  | 35,052 |  |
ASU 2016-02 |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |
Operating lease, liability |  |  |  |  | $ 17,600
Operating lease ROU asset | 17,600 |  | 17,600 |  |
U.S. |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |
Net product sales | 12,181 | 0 | 21,249 | 0 |
Ex-U.S. |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |
Net product sales | $ 31,949 | $ 21,309 | $ 56,927 | $ 38,005 |

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