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Business (Details) - USD ($)
$ / shares in Units, $ in Thousands, shares in Millions
 3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2019
Jun. 30, 2018
Dec. 31, 2018
Class of Stock [Line Items]        
Common stock issued from underwriting agreement (in shares) 18.7      
Proceeds from issuance of common stock, net of issuance costs $ 189,000 $ 188,994 $ 294,584  
Exchange agreement, aggregate principal amount $ 247,200 $ 247,200    
Shares authorized for issuance (in shares) 44.0 44.0    
Common stock, par value (in dollars per share) $ 0.01 $ 0.01   $ 0.01
Accumulated deficit $ (1,617,072) $ (1,617,072)   $ (1,412,222)
Underwritten Offering        
Class of Stock [Line Items]        
Stock issued (in dollars per share) $ 10.75 $ 10.75