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Business (Details) - USD ($) $ / shares in Units, $ in Thousands, shares in Millions | 3 Months Ended | 9 Months Ended |
--- | --- | --- | ---
Jun. 30, 2019 | Sep. 30, 2019 | Sep. 30, 2018 | Dec. 31, 2018
Class of Stock [Line Items] |  |  |  |
Common stock issued from underwriting agreement (in shares) | 18.7 |  |  |
Proceeds from issuance of common stock, net of issuance costs | $ 189,000 | $ 188,994 | $ 294,584 |
Exchange agreement, aggregate principal amount |  | $ 247,200 |  |
Shares authorized for issuance (in shares) |  | 44.0 |  |
Common stock, par value (in dollars per share) |  | $ 0.01 |  | $ 0.01
Accumulated deficit |  | $ (1,678,881) |  | $ (1,412,222)
Underwritten Offering |  |  |  |
Class of Stock [Line Items] |  |  |  |
Stock issued (in dollars per share) | $ 10.75 |  |  |

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