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Summary of Significant Accounting Policies (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Jan. 01, 2019
New Accounting Pronouncements or Change in Accounting Principle [Line Items]          
Allowance for doubtful accounts receivable $ 200   $ 200    
Net product sales 48,768 $ 20,596 126,944 $ 58,601  
Operating lease, liability 56,042   56,042    
Operating lease ROU asset 35,814   35,814    
ASU 2016-02          
New Accounting Pronouncements or Change in Accounting Principle [Line Items]          
Operating lease, liability         $ 17,600
Operating lease ROU asset 17,600   17,600    
U.S.          
New Accounting Pronouncements or Change in Accounting Principle [Line Items]          
Net product sales 15,411 757 36,660 757  
Ex-U.S.          
New Accounting Pronouncements or Change in Accounting Principle [Line Items]          
Net product sales $ 33,357 $ 19,839 $ 90,284 $ 57,844