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Cover Page - USD ($)
 12 Months Ended
Dec. 31, 2019
Feb. 19, 2020
Jun. 30, 2019
Cover page.      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2019    
Document Transition Report false    
Entity File Number 001-33497    
Entity Registrant Name Amicus Therapeutics, Inc.    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 71-0869350    
Entity Address, Address Line One 1 Cedar Brook Drive,    
Entity Address, City or Town Cranbury,    
Entity Address, State or Province NJ    
Entity Address, Postal Zip Code 08512    
City Area Code (609)    
Local Phone Number 662-2000    
Title of 12(b) Security Common Stock, par value $0.01 per share    
Trading Symbol FOLD    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer Yes    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Large Accelerated Filer    
Entity Small Business false    
Entity Emerging Growth Company false    
Entity Shell Company false    
Entity Public Float     $ 3,147,432,201
Entity Common Stock, Shares Outstanding   257,244,659  
Documents Incorporated by Reference
DOCUMENTS INCORPORATED BY REFERENCE: Portions of the Proxy Statement for the registrant's 2020 Annual Meeting of Stockholders which is to be filed subsequent to the date hereof are incorporated by reference into Part III of this Annual Report on Form 10-K.
    
Entity Central Index Key 0001178879    
Amendment Flag false    
Current Fiscal Year End Date --12-31    
Document Fiscal Year Focus 2019    
Document Fiscal Period Focus FY