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Share based Compensation (Tables)
 12 Months Ended
Dec. 31, 2019
Share-based Payment Arrangement [Abstract]  
Schedule of Fair Value of Options
The fair value of the stock options granted is estimated on the date of grant using a Black-Scholes option pricing model with the following weighted-average assumptions:
 
 
Years Ended
December 31,
 
 
2019
 
2018
 
2017
Expected stock price volatility
 
74.1
%
 
78.6
%
 
82.8
%
Risk free interest rate
 
2.4
%
 
2.4
%
 
2.0
%
Expected life of options (years) (1)
 
5.68

 
5.62

 
6.18

Expected annual dividend per share
 
$
0.00

 
$
0.00

 
$
0.00


______________________________________
(1) The average expected life is determined using actual historical data.
Schedule of Stock Options Activity
A summary of the Company's stock options for the year ended December 31, 2019 were as follows:
 
Number of
Shares
 
Weighted
Average
Exercise
Price
 
Weighted
Average
Remaining
Years
 
Aggregate
Intrinsic
Value
 
(in thousands)
 
 
 
 
 
(in millions)
Options outstanding, December 31, 2016
15,497.5

 
$
7.37

 
 
 
 
Granted
3,695.3

 
$
7.17

 
 
 
 
Exercised
(2,878.7
)
 
$
5.67

 
 
 
 
Forfeited
(1,133.0
)
 
$
9.55

 
 
 
 
Options outstanding, December 31, 2017
15,181.1

 
$
7.48

 
 
 
 
Granted
2,348.0

 
$
14.96

 
 
 
 
Exercised
(1,398.0
)
 
$
6.54

 
 
 
 
Forfeited
(313.1
)
 
$
9.55

 
 
 
 
Expired
(8.0
)
 
$
10.76

 
 
 
 
Options outstanding, December 31, 2018
15,810.0

 
$
8.63

 
 
 
 
Granted
4,091.0

 
$
10.29

 
 
 
 
Exercised
(1,967.0
)
 
$
5.83

 
 
 
 
Forfeited
(879.0
)
 
$
11.07

 
 
 
 
Expired
(331.0
)
 
$
13.38

 
 
 
 
Options outstanding, December 31, 2019
16,724.0

 
$
9.15

 
6.4
 
$
30.8

Vested and unvested expected to vest, December 31, 2019
16,111.2

 
$
9.08

 
6.3
 
$
30.6

Exercisable at December 31, 2019
10,646.5

 
$
8.33

 
5.1
 
$
27.0
Schedule of Non-Vested RSU Activity under the Plan A summary of non-vested RSU activity under the Plan for the year ended December 31, 2019 is as follows:
 
Number of
Share
 
Weighted
Average Grant
Date Fair
Value
 
Weighted
Average
Remaining
Years
 
Aggregate
Intrinsic
Value
 
(in thousands)
 
 
 
 
 
(in millions)
Non-vested units as of December 31, 2017
2,575.1

 
$
5.85

 
 
 
 
Granted
1,811.9

 
$
16.11

 
 
 
 
Vested
(530.0
)
 
$
6.01

 
 
 
 
Forfeited
(145.0
)
 
$
9.65

 
 
 
 
Non-vested units as of December 31, 2018
3,712.0

 
$
10.59

 
 
 
 
Granted
3,526.0

 
$
10.92

 
 
 
 
Vested
(921.0
)
 
$
8.49

 
 
 
 
Forfeited
(525.0
)
 
$
10.52

 
 
 
 
Non-vested units as of December 31, 2019
5,792.0

 
$
11.18

 
2.4
 
$
56.4
Schedule of Equity Compensation Expenses
The following table summarizes information related to compensation expense recognized in the Consolidated Statements of Operations related to the equity awards:
 
 
Years Ended December 31,
(in thousands)
 
2019
 
2018
 
2017
Equity compensation expense recognized in:
 
 
 
 
 
 
Research and development expense
 
$
17,575

 
$
11,740

 
$
10,328

Selling, general, and administrative expense
 
26,855

 
17,520

 
12,773

Total equity compensation expense
 
$
44,430

 
$
29,260

 
$
23,101