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Selected Quarterly Financial Data (Unaudited)
 12 Months Ended
Dec. 31, 2019
Quarterly Financial Information Disclosure [Abstract]  
Selected Quarterly Financial Data (Unaudited) Selected Quarterly Financial Data (Unaudited)
 
 
Quarters Ended
(in thousands except per share data)

 
March 31
 
June 30
 
September 30
 
December 31
2019
 
 
 
 
 
 
 
 
Net product sales
 
$
34,046

 
$
44,130

 
$
48,768

 
$
55,293

Net loss
 
$
(120,299
)
 
$
(84,551
)
 
$
(61,809
)
 
$
(89,729
)
Basic and diluted net loss per common share (1)
 
$
(0.56
)
 
$
(0.36
)
 
$
(0.24
)
 
$
(0.35
)
2018
 
 
 
 
 
 
 
 
Net product sales
 
$
16,696

 
$
21,309

 
$
20,596

 
$
32,644

Net loss
 
$
(49,916
)
 
$
(61,833
)
 
$
(159,163
)
 
$
(78,083
)
Basic and diluted net loss per common share (1)
 
$
(0.28
)
 
$
(0.33
)
 
$
(0.84
)
 
$
(0.43
)
______________________________
(1) Per common share amounts for the quarters and full years have been calculated separately. Accordingly, quarterly amounts do not add to the annual amounts because of differences on the weighted-average common shares outstanding during each period principally due to the effect of the Company issuing shares of its common stock during the year.