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Summary of Significant Accounting Policies - Revenue by Geographical Area (Details) - USD ($) $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2019	Sep. 30, 2019	Jun. 30, 2019	Mar. 31, 2019	Dec. 31, 2018	Sep. 30, 2018	Jun. 30, 2018	Mar. 31, 2018	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017
Disaggregation of Revenue [Line Items]
Net product sales	$ 55,293	$ 48,768	$ 44,130	$ 34,046	$ 32,644	$ 20,596	$ 21,309	$ 16,696	$ 182,237	$ 91,245	$ 36,930
U.S.
Disaggregation of Revenue [Line Items]
Net product sales									52,478	7,223
Ex-U.S.
Disaggregation of Revenue [Line Items]
Net product sales									$ 129,759	$ 84,022
Largest Customer | Customer Concentration Risk | Net product sales
Disaggregation of Revenue [Line Items]
Concentration risk, percentage									22.00%
Largest Customer | Customer Concentration Risk | Accounts receivable
Disaggregation of Revenue [Line Items]
Concentration risk, percentage									11.00%

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