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v3.20.1

Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2020 | Mar. 31, 2019
Operating activities |  |
Net loss | $ (88,948) | $ (120,299)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Amortization of debt discount and deferred financing | 231 | 1,649
Depreciation and amortization | 1,764 | 991
Stock-based compensation | 12,596 | 12,744
Loss on exchange of convertible debt | 0 | 36,123
Non-cash changes in the fair value of contingent consideration payable | 931 | 1,383
Foreign currency remeasurement loss | 10,662 | 325
Changes in operating assets and liabilities: |  |
Accounts receivable | (8,358) | (1,001)
Inventories | (251) | 345
Prepaid expenses and other current assets | 4,016 | 3,059
Accounts payable and accrued expenses | (35,251) | (8,858)
Other non-current assets and liabilities | (5,334) | (3,507)
Deferred reimbursements | 0 | (1,500)
Net cash used in operating activities | (107,942) | (78,546)
Investing activities |  |
Sale and redemption of marketable securities | 106,140 | 135,187
Purchases of marketable securities | (12,088) | (52,178)
Capital expenditures | (806) | (2,944)
Net cash provided by investing activities | 93,246 | 80,065
Financing activities |  |
Payment of finance leases | (21) | (75)
Purchase of vested restricted stock units | (7,543) | (1,938)
Proceeds from termination of capped call confirmations | 0 | 14,632
Proceeds from exercise of stock options | 6,077 | 3,953
Proceeds of exercise of warrants | 0 | 812
Net cash (used in) provided by financing activities | (1,487) | 17,384
Effect of exchange rate changes on cash, cash equivalents, and restricted cash | (4,265) | (2,350)
Net (decrease) increase in cash, cash equivalents, and restricted cash at the end of the period | (20,448) | 16,553
Cash, cash equivalents, and restricted cash at beginning of period | 146,341 | 82,375
Cash, cash equivalents, and restricted cash at the end of period | 125,893 | 98,928
Supplemental disclosures of cash flow information |  |
Tenant improvements paid through lease incentives | 254 | 0
Cash paid during the period for interest | 3,693 | 4,846
Contingent consideration paid in shares | 0 | 9,316
Capital expenditures unpaid at the end of period | $ 589 | $ 0

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