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Selected Quarterly Financial Data (Unaudited)
 12 Months Ended
Dec. 31, 2020
Quarterly Financial Information Disclosure [Abstract]  
Selected Quarterly Financial Data (Unaudited) Selected Quarterly Financial Data (Unaudited)
Quarters Ended
(in thousands except per share data)March 31June 30September 30December 31
2020
Net product sales$60,525 $62,353 $67,437 $70,571 
Net loss$(88,948)$(52,492)$(64,011)$(71,401)
Basic and diluted net loss per common share (1)
$(0.35)$(0.20)$(0.25)$(0.27)
2019
Net product sales$34,046 $44,130 $48,768 $55,293 
Net loss$(120,299)$(84,551)$(61,809)$(89,729)
Basic and diluted net loss per common share (1)
$(0.56)$(0.36)$(0.24)$(0.35)
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(1) Per common share amounts for the quarters and full years have been calculated separately. Accordingly, quarterly amounts do not add to the annual amounts because of differences on the weighted-average common shares outstanding during each period principally due to the effect of the Company issuing shares of its common stock during the year.