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Share based Compensation (Tables)

12 Months Ended

Dec. 31, 2020

Share-based Payment Arrangement [Abstract]

Schedule of Fair Value of Options

The fair value of the stock options granted is estimated on the date of grant using a Black-Scholes option pricing model with the following weighted-average assumptions:

						Years Ended December 31,
						2020						2019						2018
Expected stock price volatility						75.1		%				74.1		%				78.6		%
Risk free interest rate						1.6		%				2.4		%				2.4		%
Expected life of options (years)						5.67						5.68						5.62
Expected annual dividend per share						$	0.00					$	0.00					$	0.00

Schedule of Stock Options Activity

A summary of the Company's stock options for the year ended December 31, 2020 were as follows:

			Number of Shares						Weighted Average Exercise Price						Weighted Average Remaining Years						Aggregate Intrinsic Value
			(in thousands)																		(in millions)
Options outstanding, December 31, 2017			15,181						$	7.48
Granted			2,348						$	14.96
Exercised			(1,398)						$	6.54
Forfeited			(313)						$	9.55
Expired			(8)						$	10.76
Options outstanding, December 31, 2018			15,810						$	8.63
Granted			4,091						$	10.29
Exercised			(1,967)						$	5.83
Forfeited			(879)						$	11.07
Expired			(331)						$	13.38
Options outstanding, December 31, 2019			16,724						$	9.15
Granted			4,362						$	9.98
Exercised			(5,243)						$	8.11
Forfeited			(1,376)						$	10.42
Expired			(435)						$	13.33
Options outstanding, December 31, 2020			14,032						$	9.54					6.5						$	190.1
Vested and unvested expected to vest, December 31, 2020			13,267						$	9.49					6.4						$	180.5
Exercisable at December 31, 2020			8,130						$	8.86					5.1						$	115.7

Schedule of Non-Vested RSU Activity under the Plan

A summary of non-vested RSU activity under the Plan for the year ended December 31, 2020 is as follows:

			Number of Shares						Weighted Average Grant Date Fair Value						Weighted Average Remaining Years						Aggregate Intrinsic Value
			(in thousands)																		(in millions)
Non-vested units as of December 31, 2017			2,575						$	5.85
Granted			1,812						$	16.11
Vested			(530)						$	6.01
Forfeited			(145)						$	9.65
Non-vested units as of December 31, 2018			3,712						$	10.59
Granted			3,526						$	10.92
Vested			(921)						$	8.49
Forfeited			(525)						$	10.52
Non-vested units as of December 31, 2019			5,792						$	11.18
Granted			4,692						$	11.29
Vested			(2,164)						$	10.70
Forfeited			(1,240)						$	11.14
Non-vested units as of December 31, 2020			7,080						$	11.35					2.3						$	158.0

Schedule of Equity Compensation Expenses

The following table summarizes information related to compensation expense recognized in the Consolidated Statements of Operations related to the equity awards:

						Years Ended December 31,
(in thousands)						2020						2019						2018
Equity compensation expense recognized in:
Research and development expense						$	20,817					$	17,575					$	11,740
Selling, general, and administrative expense						28,334						26,855						17,520
Total equity compensation expense						$	49,151					$	44,430					$	29,260

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