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Stockholders' Equity - Common Stock and Warrants (Details) $ / shares in Units, $ in Thousands	1 Months Ended				3 Months Ended		12 Months Ended
	Feb. 28, 2021 USD ($) $ / shares shares	Mar. 31, 2019 USD ($) $ / shares shares	Apr. 30, 2018 USD ($) $ / shares shares	Feb. 28, 2018 USD ($) $ / shares shares	Jun. 30, 2019 USD ($) $ / shares shares	Mar. 31, 2019 USD ($) $ / shares	Dec. 31, 2020 USD ($) vote $ / shares shares	Dec. 31, 2019 USD ($) $ / shares shares	Dec. 31, 2018 USD ($) shares	Jun. 30, 2018 $ / shares shares	May 31, 2018 shares
Convertible Debt
Common stock, shares authorized (in shares) | shares							500,000,000	500,000,000		500,000,000	250,000,000
Voting right for each share held, number | vote							1
Stock issued from equity financing (in shares) | shares					18,700,000
Gross cash proceeds from warrant exercises							$ 0	$ 812	$ 3,617
Net proceeds from the issuance of common stock after deducting underwriting discounts and commissions					$ 189,000		$ 0	$ 188,994	$ 294,584
Contingent consideration, milestone payment						$ 9,000
Milestone payment, stock issued as consideration						9,000
Exchange agreement, aggregate principal amount					$ 247,200
Exchange agreement, authorized (in shares) | shares					44,000,000.0
Common stock, par value (in dollars per share) | $ / shares					$ 0.01		$ 0.01	$ 0.01		$ 0.01
Common Stock
Convertible Debt
Stock issued from equity financing (in shares) | shares								18,720,930	20,239,839
Milestone payment, stock issued as consideration						$ 9,300
Underwritten Offering
Convertible Debt
Stock issued (in dollars per share) | $ / shares					$ 10.75
Common Stock
Convertible Debt
Stock issued from equity financing (in shares) | shares				20,200,000
Net proceeds from the issuance of common stock after deducting underwriting discounts and commissions				$ 294,600
Price per share of common stock issued (in dollars per share) | $ / shares				$ 15.50
Warrants
Convertible Debt
Stock issued from equity financing (in shares) | shares		101,787	453,214
Gross cash proceeds from warrant exercises		$ 800	$ 3,600
Warrants | Common Stock
Convertible Debt
Exercise price of warrants (in dollars per share) | $ / shares		$ 7.98	$ 7.98			$ 7.98
Warrants | Subsequent Event
Convertible Debt
Stock issued from equity financing (in shares) | shares	1,050,000
Gross cash proceeds from warrant exercises	$ 7,400
Warrants | Subsequent Event | Common Stock
Convertible Debt
Exercise price of warrants (in dollars per share) | $ / shares	$ 7.06

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