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Consolidated Statements of Operations (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Revenue:    
Net product sales $ 66,402 $ 60,525
Cost of goods sold 6,539 6,552
Gross profit 59,863 53,973
Operating expenses:    
Research and development 64,117 89,120
Selling, general, and administrative 46,726 40,215
Changes in fair value of contingent consideration payable 471 931
Depreciation and amortization 1,604 1,764
Total operating expenses 112,918 132,030
Loss from operations (53,055) (78,057)
Other (expense) income:    
Interest income 165 1,515
Interest expense (7,992) (3,729)
Other expense (3,200) (8,316)
Loss before income tax (64,082) (88,587)
Income tax expense (1,582) (361)
Net loss attributable to common stockholders $ (65,664) $ (88,948)
Net loss attributable to common stockholders per common share - basic and diluted (in dollars per share) $ (0.25) $ (0.35)
Weighted-average common shares outstanding - basic and diluted (in shares) 264,369,317 256,968,248