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Summary of Significant Accounting Policies (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Accounting Policies [Abstract]        
Allowance for doubtful accounts receivable $ 100   $ 100  
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Net product sales 77,413 $ 62,353 143,815 $ 122,878
U.S.        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Net product sales 23,678 20,807 44,531 38,579
Ex-U.S.        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Net product sales $ 53,735 $ 41,546 $ 99,284 $ 84,299