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Consolidated Statements of Operations (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Revenue:        
Net product sales $ 77,413 $ 62,353 $ 143,815 $ 122,878
Cost of goods sold 8,380 6,676 14,919 13,228
Gross profit 69,033 55,677 128,896 109,650
Operating expenses:        
Research and development 63,003 69,611 127,120 158,731
Selling, general, and administrative 42,276 34,657 89,002 74,872
Changes in fair value of contingent consideration payable 1,021 715 1,492 1,646
Depreciation and amortization 1,567 2,039 3,171 3,803
Total operating expenses 107,867 107,022 220,785 239,052
Loss from operations (38,834) (51,345) (91,889) (129,402)
Other income (expense):        
Interest income 50 865 215 2,380
Interest expense (8,150) (3,635) (16,142) (7,364)
Other expense 234 5,326 (2,966) (2,990)
Loss before income tax (46,700) (48,789) (110,782) (137,376)
Income tax expense (4,525) (3,703) (6,107) (4,064)
Net loss attributable to common stockholders $ (51,225) $ (52,492) $ (116,889) $ (141,440)
Net loss attributable to common stockholders per common share - basic (in dollars per share) $ (0.19) $ (0.20) $ (0.44) $ (0.55)
Net loss attributable to common stockholders per common share — diluted (in dollars per share) $ (0.19) $ (0.20) $ (0.44) $ (0.55)
Weighted average common shares outstanding - basic (in shares) 266,398,516 257,973,329 265,384,865 257,548,623
Weighted average number of shares outstanding - diluted (in shares) 266,398,516 257,973,329 265,384,865 257,548,623