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Summary of Significant Accounting Policies (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Accounting Policies [Abstract]        
Allowance for doubtful accounts receivable $ 100   $ 100  
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Net product sales 79,545 $ 67,437 223,360 $ 190,315
U.S.        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Net product sales 25,636 20,278 70,167 58,857
Ex-U.S.        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Net product sales $ 53,909 $ 47,159 $ 153,193 $ 131,458