    <SEC-DOCUMENT>0001140361-21-014545-index.html : 20210427
    <SEC-HEADER>0001140361-21-014545.hdr.sgml : 20210427
    <ACCEPTANCE-DATETIME>20210427161734
    ACCESSION NUMBER:		0001140361-21-014545
    CONFORMED SUBMISSION TYPE:	DEF 14A
    PUBLIC DOCUMENT COUNT:		24
    CONFORMED PERIOD OF REPORT:	20210610
    FILED AS OF DATE:		20210427
    DATE AS OF CHANGE:		20210427

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			AMICUS THERAPEUTICS, INC.
    		CENTRAL INDEX KEY:			0001178879
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				200422823
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEF 14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-33497
    		FILM NUMBER:		21859144

    	BUSINESS ADDRESS:
    		STREET 1:		3675 MARKET STREET
    		CITY:			PHILADELPHIA
    		STATE:			PA
    		ZIP:			19104
    		BUSINESS PHONE:		(215) 921-7600

    	MAIL ADDRESS:
    		STREET 1:		3675 MARKET STREET
    		CITY:			PHILADELPHIA
    		STATE:			PA
    		ZIP:			19104

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	AMICUS THERAPEUTICS INC
    		DATE OF NAME CHANGE:	20020729
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEF 14A
    <SEQUENCE>1
    <FILENAME>nc10021408x1_def14a.htm
    <DESCRIPTION>DEF 14A
    <TEXT>
    Document 1 - file: nc10021408x1_def14a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>amicus_leaf.jpg
    <TEXT>
    Document 2 - file: amicus_leaf.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>logo_amicus.jpg
    <TEXT>
    Document 3 - file: logo_amicus.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>nc10021408x1_bleil.jpg
    <TEXT>
    Document 4 - file: nc10021408x1_bleil.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>nc10021408x1_campbell.jpg
    <TEXT>
    Document 5 - file: nc10021408x1_campbell.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>nc10021408x1_crowley.jpg
    <TEXT>
    Document 6 - file: nc10021408x1_crowley.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>nc10021408x1_diverity.jpg
    <TEXT>
    Document 7 - file: nc10021408x1_diverity.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>nc10021408x1_esg.jpg
    <TEXT>
    Document 8 - file: nc10021408x1_esg.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>nc10021408x1_essner.jpg
    <TEXT>
    Document 9 - file: nc10021408x1_essner.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>nc10021408x1_exp.jpg
    <TEXT>
    Document 10 - file: nc10021408x1_exp.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>nc10021408x1_how2.jpg
    <TEXT>
    Document 11 - file: nc10021408x1_how2.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>nc10021408x1_kelly.jpg
    <TEXT>
    Document 12 - file: nc10021408x1_kelly.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>nc10021408x1_mcglynn.jpg
    <TEXT>
    Document 13 - file: nc10021408x1_mcglynn.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>nc10021408x1_pc1.jpg
    <TEXT>
    Document 14 - file: nc10021408x1_pc1.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>nc10021408x1_pc2.jpg
    <TEXT>
    Document 15 - file: nc10021408x1_pc2.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>nc10021408x1_piechart.jpg
    <TEXT>
    Document 16 - file: nc10021408x1_piechart.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>nc10021408x1_qr.jpg
    <TEXT>
    Document 17 - file: nc10021408x1_qr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>nc10021408x1_raab.jpg
    <TEXT>
    Document 18 - file: nc10021408x1_raab.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>nc10021408x1_sblendorio.jpg
    <TEXT>
    Document 19 - file: nc10021408x1_sblendorio.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>20
    <FILENAME>nc10021408x1_score.jpg
    <TEXT>
    Document 20 - file: nc10021408x1_score.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>21
    <FILENAME>nc10021408x1_wheeler.jpg
    <TEXT>
    Document 21 - file: nc10021408x1_wheeler.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>22
    <FILENAME>nc10021408x1_whiteman.jpg
    <TEXT>
    Document 22 - file: nc10021408x1_whiteman.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>23
    <FILENAME>nc10021408x999_sig1.jpg
    <TEXT>
    Document 23 - file: nc10021408x999_sig1.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>24
    <FILENAME>nc10021408x999_sig2.jpg
    <TEXT>
    Document 24 - file: nc10021408x999_sig2.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>