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Assets and Liabilities Measured at Fair Value (Tables)
12 Months Ended
Dec. 31, 2021
Fair Value Disclosures [Abstract]  
Summary of Assets and Liabilities Subject to Fair Value Measurements
A summary of the fair value of the Company's recurring assets and liabilities aggregated by the level in the fair value hierarchy within which those measurements fall as of December 31, 2021 are identified in the following tables:
(in thousands)Level 2Total
Assets:
Commercial paper$174,531 $174,531 
Corporate debt securities32,311 32,311 
Asset-backed securities30,056 30,056 
Money market funds5,150 5,150 
$242,048 $242,048 
(in thousands)Level 2Level 3Total
Liabilities:
Contingent consideration payable$— $20,339 $20,339 
Deferred compensation plan liability4,800 — 4,800 
$4,800 $20,339 $25,139 
A summary of the fair value of the Company's recurring assets and liabilities aggregated by the level in the fair value hierarchy within which those measurements fall as of December 31, 2020 are identified in the following tables:
(in thousands)Level 2Total
Assets:
Commercial paper$217,095 $217,095 
U.S. government agency bonds53,582 53,582 
Corporate debt securities39,513 39,513 
Asset-backed securities9,438 9,438 
Money market funds4,427 4,427 
$324,055 $324,055 
(in thousands)Level 2Level 3Total
Liabilities:
Contingent consideration payable$— $25,825 $25,825 
Deferred compensation plan liability4,078 — 4,078 
$4,078 $25,825 $29,903 
Schedule of Significant Unobservable Inputs Used in the Valuation of the Contingent Consideration Payable
The following significant unobservable inputs were used in the valuation of the contingent consideration payable of Callidus for the ATB-200 Pompe disease program:
Contingent Consideration LiabilityFair Value as of December 31, 2021Valuation TechniqueUnobservable InputRange
(in thousands)
 Discount rate7.5%
Clinical and regulatory milestones$18,883 Probability weighted discounted cash flowProbability of achievement of milestones
75%-88%
 Projected year of payments2022
Schedule of Changes in Contingent Consideration Payable
The following table shows the change in the balance of contingent consideration payable for the year ended December 31, 2021 and December 31, 2020, respectively:
Years ended December 31,
(in thousands)20212020
Balance, beginning of the period$25,825 $22,681 
Changes in fair value during the period, included in the Consolidated Statements of Operations 6,514 3,144 
Payment of contingent consideration in cash(12,000)— 
Balance, end of the period$20,339 $25,825