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Income Taxes - Loss Carryforwards (Details) $ in Millions	Dec. 31, 2021 USD ($)
Research and experimentation tax credit carryforward
Operating Loss Carryforwards [Line Items]
Tax credit carryforward amount	$ 30.3
Orphan drug tax credit carryforwards
Operating Loss Carryforwards [Line Items]
Tax credit carryforward amount	165.2
Federal
Operating Loss Carryforwards [Line Items]
Amount of net operating loss carry forwards	1,292.0
State
Operating Loss Carryforwards [Line Items]
Amount of net operating loss carry forwards	$ 1,000.0

X

- Definition

Amount of operating loss carryforward, before tax effects, available to reduce future taxable income under enacted tax laws.

+ References

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 740
-SubTopic 10
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The amount of the tax credit carryforward, before tax effects, available to reduce future taxable income under enacted tax laws.

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