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Share-Based Compensation - Expense Summary (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
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Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |
Total equity compensation expense | $ 12,463 | $ 11,736 | $ 43,114 | $ 32,090
Research and development expense |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |
Total equity compensation expense | 4,379 | 3,152 | 13,744 | 9,457
Selling, general, and administrative expense |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |
Total equity compensation expense | $ 8,084 | $ 8,584 | $ 29,370 | $ 22,633

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- Definition Amount of expense for award under share-based payment arrangement. Excludes amount capitalized. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1)(i) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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