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Summary of Significant Accounting Policies (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Allowance for doubtful accounts receivable $ 100   $ 100  
Loss on impairment of assets 0 $ 0 6,616 $ 0
Net product sales 80,731 77,413 159,446 143,815
Contractual obligation 20,000   $ 20,000  
Minimum        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Estimated useful life     3 years  
Maximum        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Estimated useful life     5 years  
U.S.        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Net product sales 27,540 23,678 $ 51,718 44,531
Ex-U.S.        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Net product sales $ 53,191 $ 53,735 $ 107,728 $ 99,284