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Consolidated Statements of Operations (Unaudited)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2022
USD ($)
shares
Jun. 30, 2022
$ / shares
Jun. 30, 2021
USD ($)
shares
Jun. 30, 2021
$ / shares
Jun. 30, 2022
USD ($)
shares
Jun. 30, 2022
$ / shares
Jun. 30, 2021
USD ($)
shares
Jun. 30, 2021
$ / shares
Revenue:                
Net product sales $ 80,731   $ 77,413   $ 159,446   $ 143,815  
Cost of goods sold 8,197   8,380   15,779   14,919  
Gross profit 72,534   69,033   143,667   128,896  
Operating expenses:                
Research and development 78,319   63,003   159,836   127,120  
Selling, general, and administrative 53,379   42,276   111,495   89,002  
Changes in fair value of contingent consideration payable 115   1,021   (1,073)   1,492  
Loss on impairment of assets 0   0   6,616   0  
Depreciation and amortization 1,334   1,567   2,745   3,171  
Total operating expenses 133,147   107,867   279,619   220,785  
Loss from operations (60,613)   (38,834)   (135,952)   (91,889)  
Other (expense) income:                
Interest income 356   50   489   215  
Interest expense (8,257)   (8,150)   (16,404)   (16,142)  
Other income 7,268   234   9,170   (2,966)  
Loss before income tax (61,246)   (46,700)   (142,697)   (110,782)  
Income tax expense (911)   (4,525)   (4,720)   (6,107)  
Net loss attributable to common stockholders $ (62,157)   $ (51,225)   $ (147,417)   $ (116,889)  
Net loss attributable to common stockholders per common share - basic (in dollars per share) | $ / shares   $ (0.21)   $ (0.19)   $ (0.51)   $ (0.44)
Net loss attributable to common stockholders per common share — diluted (in dollars per share) | $ / shares   $ (0.21)   $ (0.19)   $ (0.51)   $ (0.44)
Weighted average common shares outstanding - basic (in shares) | shares 291,970,562   266,398,516   288,646,587   265,384,865  
Weighted average number of shares outstanding - diluted (in shares) | shares 291,970,562   266,398,516   288,646,587   265,384,865