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Share-Based Compensation - Expense Summary (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
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Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |
Total equity compensation expense | $ 14,772 | $ 11,841 | $ 57,886 | $ 43,931
Research and development expense |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |
Total equity compensation expense | 5,428 | 3,775 | 19,172 | 13,232
Selling, general, and administrative expense |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |
Total equity compensation expense | $ 9,344 | $ 8,066 | $ 38,714 | $ 30,699

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- Definition Amount of expense for award under share-based payment arrangement. Excludes amount capitalized. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1)(i) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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