<SEC-DOCUMENT>0001104659-22-115118-index.html : 20221107
<SEC-HEADER>0001104659-22-115118.hdr.sgml : 20221107
<ACCEPTANCE-DATETIME>20221107071120
ACCESSION NUMBER:		0001104659-22-115118
CONFORMED SUBMISSION TYPE:	424B5
PUBLIC DOCUMENT COUNT:		3
FILED AS OF DATE:		20221107
DATE AS OF CHANGE:		20221107

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AMICUS THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001178879
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				200422823
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-262987
		FILM NUMBER:		221363699

	BUSINESS ADDRESS:	
		STREET 1:		3675 MARKET STREET
		CITY:			PHILADELPHIA
		STATE:			PA
		ZIP:			19104
		BUSINESS PHONE:		(215) 921-7600

	MAIL ADDRESS:	
		STREET 1:		3675 MARKET STREET
		CITY:			PHILADELPHIA
		STATE:			PA
		ZIP:			19104

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AMICUS THERAPEUTICS INC
		DATE OF NAME CHANGE:	20020729
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B5
<SEQUENCE>1
<FILENAME>tm2229608-1_424b5.htm
<DESCRIPTION>424B5
<TEXT>
Document 1 - file: tm2229608-1_424b5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>2
<FILENAME>tm2229608d2_ex-filingfees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 2 - file: tm2229608d2_ex-filingfees.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>lg_amicustherape-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: lg_amicustherape-4c.jpg

</DOCUMENT>
</SEC-DOCUMENT>