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Income Taxes - Loss Carryforwards (Details) $ in Millions | Dec. 31, 2022 USD ($)
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Research and experimentation tax credit carryforward |
Operating Loss Carryforwards [Line Items] |
Tax credit carryforward amount | $ 36.4
Orphan drug tax credit carryforwards |
Operating Loss Carryforwards [Line Items] |
Tax credit carryforward amount | 187.0
Federal |
Operating Loss Carryforwards [Line Items] |
Amount of net operating loss carry forwards | 1,183.0
State |
Operating Loss Carryforwards [Line Items] |
Amount of net operating loss carry forwards | $ 992.0

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- Definition Amount of operating loss carryforward, before tax effects, available to reduce future taxable income under enacted tax laws. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 3 -Subparagraph (a) -URI https://asc.fasb.org/extlink&oid=121826272&loc=d3e32559-109319 + Details
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- Definition The amount of the tax credit carryforward, before tax effects, available to reduce future taxable income under enacted tax laws. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 3 -Subparagraph (a) -URI https://asc.fasb.org/extlink&oid=121826272&loc=d3e32559-109319 + Details
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