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Summary of Significant Accounting Policies - Concentration of Credit Risk and Revenue Recognition (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Concentration Risk [Line Items]
Allowance for doubtful accounts receivable	$ 200
Net product sales	329,233	$ 305,514	$ 260,886
Galafold
Concentration Risk [Line Items]
Net product sales	$ 329,000	$ 305,500	$ 260,900
Net product sales | Customer Concentration Risk | Customer One
Concentration Risk [Line Items]
Concentration risk, percentage	27.00%	24.00%
Accounts receivable | Customer Concentration Risk | Customer One
Concentration Risk [Line Items]
Concentration risk, percentage	14.00%	14.00%

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Amount of allowance for credit loss on accounts receivable.

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