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Summary of Significant Accounting Policies - Revenue by Geographical Area (Details) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Net product sales $ 86,270 $ 78,715
U.S.    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Net product sales 28,831 24,178
Ex-U.S.    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Net product sales $ 57,439 $ 54,537