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Summary of Significant Accounting Policies - Revenue by Product and Geographical Area (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Net product sales $ 103,501 $ 81,691 $ 284,274 $ 241,137
Galafold        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Net product sales 100,733 81,631 281,177 241,056
Pombiliti + Opfolda        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Net product sales 2,768 60 3,097 81
U.S.        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Net product sales 37,801 30,222 103,760 81,940
Ex-U.S.        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Net product sales $ 65,700 $ 51,469 $ 180,514 $ 159,197