<SEC-DOCUMENT>0001104659-23-070869.txt : 20230613
<SEC-HEADER>0001104659-23-070869.hdr.sgml : 20230613
<ACCEPTANCE-DATETIME>20230613170617
ACCESSION NUMBER:		0001104659-23-070869
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		6
FILED AS OF DATE:		20230613
DATE AS OF CHANGE:		20230613
EFFECTIVENESS DATE:		20230613

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AMICUS THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001178879
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				200422823
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-272621
		FILM NUMBER:		231012063

	BUSINESS ADDRESS:	
		STREET 1:		3675 MARKET STREET
		CITY:			PHILADELPHIA
		STATE:			PA
		ZIP:			19104
		BUSINESS PHONE:		(215) 921-7600

	MAIL ADDRESS:	
		STREET 1:		3675 MARKET STREET
		CITY:			PHILADELPHIA
		STATE:			PA
		ZIP:			19104

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AMICUS THERAPEUTICS INC
		DATE OF NAME CHANGE:	20020729
</SEC-HEADER>
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<TYPE>S-8
<SEQUENCE>1
<FILENAME>tm2318498d1_s8.htm
<DESCRIPTION>S-8
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>As filed with the Securities and Exchange Commission
on June&nbsp;13, 2023</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right"><B>File No.&nbsp;333-</B>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right">&nbsp;</P>

<P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>UNITED STATES<BR>
SECURITIES AND EXCHANGE COMMISSION</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>WASHINGTON, DC 20549</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>FORM&nbsp;S-8</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>REGISTRATION STATEMENT<BR>
UNDER<BR>
THE SECURITIES ACT OF 1933</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>AMICUS THERAPEUTICS,&nbsp;INC.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Exact Name of Registrant as Specified in Its Charter)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR>
    <TD STYLE="vertical-align: top; width: 50%; padding: 0.5pt; text-align: center"><B>Delaware</B></TD>
    <TD STYLE="vertical-align: top; width: 50%; padding: 0.5pt; text-align: center"><B>71-0869350</B></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt; text-align: center">(State or Other Jurisdiction of</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt; text-align: center">(I.R.S. Employer</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt; text-align: center">Incorporation or Organization)</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt; text-align: center">Identification No.)</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>3675 Market Street, Philadelphia, PA 19104<BR>
</B>(Address of Principal Executive Office)( Zip Code)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>2023 EMPLOYEE STOCK PURCHASE PLAN</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>AMENDED AND RESTATED 2007 EQUITY INCENTIVE PLAN<BR>
</B>(Full title of the plan)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Bradley L. Campbell<BR>
Chief Executive Officer<BR>
Amicus Therapeutics,&nbsp;Inc.<BR>
3675 Market Street</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Philadelphia, PA 19104</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Name and address of Agent for Service)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(215) 921-7600<BR>
</B>(Telephone Number of agent for service)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Copy to:</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Scott R. Jones, Esquire<BR>
</B>Troutman Pepper Hamilton Sanders LLP<BR>
400 Berwyn Park<BR>
899 Cassatt Road<BR>
Berwyn, Pennsylvania 19312-1183<BR>
(610) 640-7800</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Indicate by check mark whether the registrant
is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company.
See the definitions of &ldquo;large accelerated filer,&rdquo; &ldquo;accelerated filer,&rdquo; &ldquo;smaller reporting company,&rdquo;
and &ldquo;emerging growth company&rdquo; in Rule&nbsp;12b-2 of the Exchange Act.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR>
    <TD STYLE="vertical-align: top; width: 51%; padding: 0.5pt 0.5pt 0.5pt 72.25pt">Large accelerated filer <FONT STYLE="font-family: Wingdings">&#120;</FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 1%; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; width: 48%; padding: 0.5pt 72.25pt 0.5pt 0.5pt">Accelerated filer <FONT STYLE="font-family: Wingdings"><FONT STYLE="font-family: Wingdings">&#168;</FONT></FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt 0.5pt 0.5pt 72.25pt">Non-accelerated filer <FONT STYLE="font-family: Wingdings"><FONT STYLE="font-family: Wingdings">&#168;</FONT></FONT></TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt 72.25pt 0.5pt 0.5pt">Smaller reporting company <FONT STYLE="font-family: Wingdings"><FONT STYLE="font-family: Wingdings">&#168;</FONT></FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt 72.25pt 0.5pt 0.5pt">Emerging growth company <FONT STYLE="font-family: Wingdings"><FONT STYLE="font-family: Wingdings">&#168;</FONT></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">If an emerging growth company, indicate by check
mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting
standards provided pursuant to Section&nbsp;7(a)(2)(B)&nbsp;of the Securities Act. <FONT STYLE="font-family: Wingdings">o</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>EXPLANATORY NOTE</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">This Registration Statement
on Form&nbsp;S-8 is being filed for the purpose of (i)&nbsp;registering the offer and sale of 2,850,000 shares of Common Stock for issuance
under the Amicus Therapeutics,&nbsp;Inc. 2023 Employee Stock Purchase Plan (&ldquo;ESPP&rdquo;) and (ii)&nbsp;registering an additional
5,000,000 shares of Common Stock that were added to the shares authorized for issuance under the Registrant&rsquo;s Amended and Restated
2007 Equity Incentive Plan (&ldquo;Equity Incentive Plan&rdquo;) for which a Registration Statement on Form&nbsp;S-8 relating to the
same employee benefit plan is effective. Pursuant to General Instruction E to Form&nbsp;S-8, with respect to the Equity Incentive Plan,
the contents of the Registration Statements on Form&nbsp;S-8 (File Nos. 333-145305, 333-157219, 333-174900, 333-233153, 333-243779, 333-257289
and 333-265531) filed with the Securities and Exchange Commission (the &ldquo;Commission&rdquo;) on <A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000095012307011217/y37940sv8.htm" STYLE="-sec-extract: exhibit">August&nbsp;10, 2007</A>, <A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000089322009000251/w72683sv8.htm" STYLE="-sec-extract: exhibit">February&nbsp;10, 2009</A>, <A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000095012311059118/c18760sv8.htm">June&nbsp;15, 2011</A>, <A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000110465919044956/a19-16819_1s8.htm">August&nbsp;8, 2019</A>, <A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000110465920092862/tm2026897d1_s8.htm" STYLE="-sec-extract: exhibit">August&nbsp;11, 2020</A>, <A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000110465921084168/tm2119601d2_s8.htm" STYLE="-sec-extract: exhibit">June&nbsp;22, 2021</A> and <A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000110465922070177/tm2218031d2_s8.htm" STYLE="-sec-extract: exhibit">June&nbsp;10, 2022</A>, respectively, are incorporated
herein by reference except to the extent supplemented, amended or superseded by the information set forth herein. Only those items of
Form&nbsp;S-8 containing new information not contained in the earlier registration statements are presented herein.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>PART&nbsp;I</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>INFORMATION REQUIRED IN THE SECTION&nbsp;10(a)&nbsp;PROSPECTUS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The document(s)&nbsp;containing the information
specified in Part&nbsp;I with respect to the ESPP will be sent or given to employees as specified by Rule&nbsp;428(b)(1)&nbsp;of the Securities
Act of 1933, as amended (the &ldquo;Securities Act&rdquo;). Such documents are not being filed with the Securities Exchange Commission
(the &ldquo;Commission&rdquo;) either as part of this Registration Statement or as prospectuses or prospectus supplements pursuant to
Rule&nbsp;424 of the Securities Act. Such documents and the documents incorporated by reference in this Registration Statement pursuant
to Item 3 of Part&nbsp;II hereof, taken together, constitute a prospectus that meets the requirements of Section&nbsp;10(a)&nbsp;of the
Securities Act.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>PART&nbsp;II<BR>
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Item 3. Incorporation of Documents by Reference.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The following documents of
the Registrant filed with the Commission are incorporated by reference in this Registration Statement as of their respective dates:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px">&nbsp;</TD>
    <TD STYLE="width: 24px">(a)</TD>
    <TD STYLE="text-align: justify">The <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/1178879/000117887923000004/fold-20221231.htm" STYLE="-sec-extract: exhibit">Registrant&rsquo;s Annual Report on Form&nbsp;10-K for the fiscal year ended December&nbsp;31, 2022, filed with the Commission on March&nbsp;1, 2023</A>;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px">&nbsp;</TD>
    <TD STYLE="width: 24px; text-align: justify">(b)</TD>
    <TD STYLE="text-align: justify">The <A HREF="http://www.sec.gov/ix?doc=/Archives/edgar/data/1178879/000114036123020594/ny20007756x1_def14a.htm" STYLE="-sec-extract: exhibit">Registrant&rsquo;s Definitive Proxy Statement on Schedule 14A, filed with the Commission on April&nbsp;26, 2023</A>;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px">&nbsp;</TD>
    <TD STYLE="width: 24px; text-align: justify">(c)</TD>
    <TD STYLE="text-align: justify">The <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/1178879/000117887923000009/fold-20230331.htm" STYLE="-sec-extract: exhibit">Registrant&rsquo;s Quarterly Report on Form&nbsp;10-Q for the quarter ended March&nbsp;31, 2023 filed with the Commission on May&nbsp;10, 2023</A>;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px">&nbsp;</TD>
    <TD STYLE="width: 24px; text-align: justify">(d)</TD>
    <TD STYLE="text-align: justify">The Registrant&rsquo;s Current Reports on Form&nbsp;8-K (other than portions thereof furnished under
    Item 2.02 or Item 7.01 of Form&nbsp;8-K and exhibits accompanying such reports that are related to such items) filed on <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/1178879/000110465923048708/tm2313469d1_8k.htm" STYLE="-sec-extract: exhibit">April&nbsp;24, 2023</A>, <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/1178879/000110465923059851/tm2315589d1_8k.htm" STYLE="-sec-extract: exhibit">May&nbsp;12, 2023</A> and <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/1178879/000110465923070827/tm2318498d2_8k.htm" STYLE="-sec-extract: exhibit">June&nbsp;13, 2023</A>; and</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px">&nbsp;</TD>
    <TD STYLE="width: 24px; text-align: justify">(e)</TD>
    <TD STYLE="text-align: justify">The Description of the Registrant&rsquo;s Securities Registered Pursuant to Section&nbsp;12 of the
    Securities Exchange Act of 1934, contained in <A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000117887920000015/exhibit48descriptionof.htm" STYLE="-sec-extract: exhibit">Exhibit&nbsp;4.8</A> to the Registrant&rsquo;s Annual Report on Form&nbsp;10-K for the
    fiscal year ended December&nbsp;31, 2019, as filed with the Commission on March&nbsp;2, 2020, which updates the description of the
    Registrant&rsquo;s Common Stock contained in the Registrant&rsquo;s registration statement on&nbsp;Form&nbsp;8-A&nbsp;dated May&nbsp;23,
    2007, as amended by any subsequent amendment or report filed for the purpose of updating such description.</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">All documents subsequently
filed by the Registrant pursuant to Sections 13(a), 13(c), 14 and 15(d)&nbsp;of the Exchange Act prior to the filing of a post-effective
amendment which indicates that all securities offered hereby have been sold or which deregisters all securities then remaining unsold,
shall be deemed to be incorporated by reference into this Registration Statement and to be a part hereof from the date of filing of such
documents; provided, however, that documents or information deemed to have been furnished and not filed in accordance with Commission
rules&nbsp;shall not be deemed incorporated by reference into this Registration Statement. Any statement contained herein or in a document,
all or a portion of which is incorporated or deemed to be incorporated by reference herein, shall be deemed to be modified or superseded
for purposes of this Registration Statement to the extent that a statement contained herein or in any other subsequently filed document
which also is or is deemed to be incorporated by reference herein modifies or supersedes such statement. Any such statement so modified
or superseded shall not be deemed, except as so modified or amended, to constitute a part of this Registration Statement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Item 6. Indemnification of Directors and Officers.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Section&nbsp;102 of the Delaware
General Corporation Law permits a corporation to eliminate the personal liability of directors and certain officers of a corporation to
the corporation or its stockholders for monetary damages for a breach of fiduciary duty as a director or applicable officer, except where
the director or officer breached his or her duty of loyalty, failed to act in good faith, engaged in intentional misconduct or knowingly
violated a law, obtained an improper personal benefit, with respect to directors, authorized the payment of a dividend or approved a stock
repurchase in violation of Delaware corporate law or, with respect to officers, an action is by or in the right of the corporation. The
Registrant&rsquo;s restated certificate of incorporation provides that no director or applicable officer of the Registrant shall be personally
liable to it or its stockholders for monetary damages for any breach of fiduciary duty as director, notwithstanding any provision of law
imposing such liability, except to the extent that the Delaware General Corporation Law prohibits the elimination or limitation of liability
of directors for breaches of fiduciary duty.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Section&nbsp;145 of the Delaware
General Corporation Law provides that a corporation has the power to indemnify any person who was or is a party or is threatened to be
made a party to any threatened, pending or completed action, suit or proceeding, whether civil, criminal, administrative or investigative,
by reason of the fact that the person is or was a director, officer, employee or agent of the corporation, or is or was serving at the
request of the corporation as a director, officer, employee or agent of another corporation, partnership, joint venture, trust or other
enterprise, against expenses (including attorneys&rsquo; fees), judgments, fines and amounts paid in settlements actually and reasonably
incurred by the person in connection with an action, suit or proceeding to which he or she is or is threatened to be made a party by reason
of such position, if such person acted in good faith and in a manner he or she reasonably believed to be in or not opposed to the best
interests of the corporation, and, in any criminal action or proceeding, had no reasonable cause to believe his or her conduct was unlawful,
except that, in the case of actions brought by or in the right of the corporation, no indemnification shall be made with respect to any
claim, issue or matter as to which such person shall have been adjudged to be liable to the corporation unless and only to the extent
that the Delaware Court of Chancery or other adjudicating court determines that, despite the adjudication of liability but in view of
all of the circumstances of the case, such person is fairly and reasonably entitled to indemnity for such expenses which the Delaware
Court of Chancery or such other court shall deem proper.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The Registrant&rsquo;s restated
certificate of incorporation provides that the Registrant will, to the fullest extent permitted by Section&nbsp;145 of the Delaware General
Corporation Law and the Registrant&rsquo;s by-laws (each as amended from time to time), indemnify each person who was or is a party or
is threatened to be made a party to any threatened, pending or completed action, suit or proceeding, whether civil, criminal, administrative
or investigative, by reason of the fact that he or she is or was, or has agreed to become, a director or officer of the Registrant, or
is or was serving, or has agreed to serve, at the request of the Registrant, as a director, officer, partner, or trustee of, or in a similar
capacity with, another corporation, partnership, joint venture, trust or other enterprise, including any employee benefit plan (all such
persons being referred to hereafter as an &ldquo;Indemnitee&rdquo;), or by reason of any action alleged to have been taken or omitted
in such capacity, against all expenses (including attorneys&rsquo; fees), judgments, fines and amounts paid in settlement actually and
reasonably incurred by, or on behalf of, the Indemnitee in connection with such action, suit or proceeding and any appeal therefrom. Such
indemnification may include payment by the Registrant of expenses in defending an action or proceeding in advance of the final disposition
of such action or proceeding upon receipt of an undertaking by the Indemnitee (such undertaking acceptable by the Registrant without reference
to the financial ability of the Indemnitee) to repay such payment if it is ultimately determined that the Indemnitee is not entitled to
indemnification under the Registrant&rsquo;s restated certificate of incorporation; however, the Registrant will not indemnify any person
seeking indemnification in connection with a proceeding (or part thereof) initiated by such person, unless such initiation was approved
by the Registrant&rsquo;s board of directors. Also, the indemnification rights provided in the Registrant&rsquo;s restated certificate
of incorporation (i)&nbsp;are not exclusive of any other rights to which those indemnified may be entitled under any law, agreement or
vote of stockholders or disinterested directors or otherwise, and (ii)&nbsp;will inure to the benefit of the heirs, executors and administrators
of such persons. The Registrant may, to the extent authorized from time to time by its board of directors, grant indemnification rights
to other employees of the Registrant or other persons serving the Registrant and such rights may be equivalent to, or greater or less
than, those set forth in the Registrant&rsquo;s restated certificate of incorporation.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The Registrant has entered
into indemnification agreements with each of its directors. These agreements, among other things, require the Registrant to indemnify
each director to the fullest extent permitted by Delaware law, including indemnification of expenses such as attorneys&rsquo; fees, judgments,
fines and settlement amounts incurred by the director in any action or proceeding, including any action or proceeding by or in right of
the Registrant, arising out of the person&rsquo;s services as a director.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The Registrant maintains a
general liability insurance policy that covers certain liabilities of the Registrant&rsquo;s directors and officers arising out of claims
based on acts or omissions in their capacities as directors or officers. In any underwriting agreement that the Registrant enters into
in connection with the sale of common stock being registered hereby, the underwriters will agree to indemnify, under certain conditions,
the Registrant, its directors, its officers and persons who control the Registrant within the meaning of the Securities Act, against certain
liabilities.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Item 8. Exhibits.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="width: 7%; border-bottom: black 1pt solid; padding: 0.5pt 0.5pt 1pt"><B>Exhibit<BR>
    Number</B></TD>
    <TD STYLE="width: 2%; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="width: 6%; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="width: 2%; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="width: 83%; border-bottom: black 1pt solid; padding: 0.5pt 0.5pt 1pt; text-align: center"><B>Description</B></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000119312512085717/d299897dex31.htm" STYLE="-sec-extract: exhibit">4.1</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000119312512085717/d299897dex31.htm" STYLE="-sec-extract: exhibit">(1)</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000119312512085717/d299897dex31.htm" STYLE="-sec-extract: exhibit">Restated Certificate of Incorporation of the Registrant</A></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000110465915044580/a15-13880_1ex3d1.htm" STYLE="-sec-extract: exhibit">4.2</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000110465915044580/a15-13880_1ex3d1.htm" STYLE="-sec-extract: exhibit">(2)</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000110465915044580/a15-13880_1ex3d1.htm" STYLE="-sec-extract: exhibit">Certificate of Amendment to the Restated Certificate of Incorporation of the Registrant</A></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000110465918039068/a18-15070_1ex3d1.htm#Exhibit3_1_045312" STYLE="-sec-extract: exhibit">4.3</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000110465918039068/a18-15070_1ex3d1.htm#Exhibit3_1_045312" STYLE="-sec-extract: exhibit">(3)</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000110465918039068/a18-15070_1ex3d1.htm#Exhibit3_1_045312" STYLE="-sec-extract: exhibit">Certificate of Amendment to the Restated Certificate of Incorporation of the Registrant</A></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000110465923070827/tm2318498d2_ex3-1.htm" STYLE="-sec-extract: exhibit">4.4</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000110465923070827/tm2318498d2_ex3-1.htm" STYLE="-sec-extract: exhibit">(4)</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000110465923070827/tm2318498d2_ex3-1.htm" STYLE="-sec-extract: exhibit">Certificate of Amendment to the Restated Certificate of Incorporation of the Registrant</A></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000095012307004755/y32191exv3w3.txt" STYLE="-sec-extract: exhibit">4.5</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000095012307004755/y32191exv3w3.txt" STYLE="-sec-extract: exhibit">(5)</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000095012307004755/y32191exv3w3.txt" STYLE="-sec-extract: exhibit">Restated By-laws of the Registrant</A></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000095012307007596/y32191a2exv4w1.txt" STYLE="-sec-extract: exhibit">4.6</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000095012307007596/y32191a2exv4w1.txt" STYLE="-sec-extract: exhibit">(6)</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000095012307007596/y32191a2exv4w1.txt" STYLE="-sec-extract: exhibit">Specimen Stock Certificate evidencing shares of common stock</A></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="tm2318498d1_ex5-1.htm" STYLE="-sec-extract: exhibit">5.1</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="tm2318498d1_ex5-1.htm" STYLE="-sec-extract: exhibit">Opinion of Troutman Pepper Hamilton Sanders LLP</A></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="tm2318498d1_ex23-1.htm" STYLE="-sec-extract: exhibit">23.1</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="tm2318498d1_ex23-1.htm" STYLE="-sec-extract: exhibit">Consent of Ernst&nbsp;&amp; Young LLP,&nbsp;Independent Registered Public Accounting Firm</A></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="tm2318498d1_ex5-1.htm" STYLE="-sec-extract: exhibit">23.2</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="tm2318498d1_ex5-1.htm" STYLE="-sec-extract: exhibit">Consent of Troutman Pepper Hamilton Sanders LLP (included in Exhibit&nbsp;5.1)</A></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="#sig">24.1</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="#sig">Power of Attorney (included on the signature page)</A></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/1178879/000114036123020594/ny20007756x1_def14a.htm" STYLE="-sec-extract: exhibit">99.1</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/1178879/000114036123020594/ny20007756x1_def14a.htm" STYLE="-sec-extract: exhibit">(7)</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/1178879/000114036123020594/ny20007756x1_def14a.htm" STYLE="-sec-extract: exhibit">Amended and Restated 2007 Equity Incentive Plan</A></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000110465916164572/a16-23950_1ex10d1.htm" STYLE="-sec-extract: exhibit">99.2</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000110465916164572/a16-23950_1ex10d1.htm" STYLE="-sec-extract: exhibit">(8)</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000110465916164572/a16-23950_1ex10d1.htm" STYLE="-sec-extract: exhibit">Form&nbsp;of Performance-Based Restricted Stock Unit Award Agreement under the Amended and Restated 2007
    Equity Incentive Plan</A></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000117887921000004/formofrestrictedstockunita.htm" STYLE="-sec-extract: exhibit">99.3</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000117887921000004/formofrestrictedstockunita.htm" STYLE="-sec-extract: exhibit">(9)</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000117887921000004/formofrestrictedstockunita.htm" STYLE="-sec-extract: exhibit">Form&nbsp;of Board Restricted Stock Unit Award Agreement under the Amended and Restated 2007 Equity Incentive
    Plan</A></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000117887921000004/formofboardstockoptionawar.htm" STYLE="-sec-extract: exhibit">99.4</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000117887921000004/formofboardstockoptionawar.htm" STYLE="-sec-extract: exhibit">(10)</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000117887921000004/formofboardstockoptionawar.htm" STYLE="-sec-extract: exhibit">Form&nbsp;of Board Stock Option Award Agreement under the Amended and Restated 2007 Equity Incentive Plan</A></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000117887921000004/formofstockoptionawardagre.htm" STYLE="-sec-extract: exhibit">99.5</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000117887921000004/formofstockoptionawardagre.htm" STYLE="-sec-extract: exhibit">(11)</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000117887921000004/formofstockoptionawardagre.htm" STYLE="-sec-extract: exhibit">Form&nbsp;of Stock Option Award Agreement under the Amended and Restated 2007 Equity Incentive Plan</A></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000117887922000006/fold-12312021xex1025.htm" STYLE="-sec-extract: exhibit">99.6</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000117887922000006/fold-12312021xex1025.htm" STYLE="-sec-extract: exhibit">(12)</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1178879/000117887922000006/fold-12312021xex1025.htm" STYLE="-sec-extract: exhibit">Form&nbsp;of Restricted Stock Unit Award Agreement under the Amended and Restated 2007 Equity Incentive
    Plan</A></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt"><A HREF="tm2318498d1_ex-filingfees.htm" STYLE="-sec-extract: exhibit">107.1</A></TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt"><A HREF="tm2318498d1_ex-filingfees.htm" STYLE="-sec-extract: exhibit">Filing
Fee Table</A></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">(1)</TD>
    <TD>Incorporated by reference to Exhibit&nbsp;3.1 to the Registrant&rsquo;s Annual Report on Form&nbsp;10-K filed on February&nbsp;28, 2012.</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">(2)</TD>
    <TD>Incorporated by reference to Exhibit&nbsp;3.1 to the Registrant&rsquo;s Current Report on Form&nbsp;8-K filed on June&nbsp;10, 2015.</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">(3)</TD>
    <TD>Incorporated by reference to Exhibit&nbsp;3.1 to the Registrant&rsquo;s Current Report on Form&nbsp;8-K filed on June&nbsp;8, 2018.</TD></TR>
</TABLE>

<P STYLE="margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">(4)</TD>
    <TD>Incorporated by reference to Exhibit&nbsp;3.1 to the Registrant&rsquo;s Current Report on Form&nbsp;8-K filed on June&nbsp;13, 2023.</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">(5)</TD>
    <TD>Incorporated by reference to Exhibit 3.4
to the Registrant&rsquo;s Registration Statement on Form S-1/A (Registration No. 333-141700), as amended, originally filed on April 27, 2007.</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">(6)</TD>
    <TD>Incorporated by reference to Exhibit&nbsp;4.1 to the Registrant&rsquo;s Registration Statement on Form&nbsp;S-1/A (Registration No.&nbsp;333-141700), filed with the SEC on May&nbsp;17, 2007.</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">(7)</TD>
    <TD>Incorporated by reference to Exhibit&nbsp;A to the Registrant&rsquo;s Definitive Proxy Statement on Schedule 14A filed on April&nbsp;26, 2023.</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">(8)</TD>
    <TD>Incorporated by reference to Exhibit&nbsp;10.1 to the Registrant&rsquo;s Current Report on Form&nbsp;8-K filed on December&nbsp;30, 2016.</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">(9)</TD>
    <TD>Incorporated by reference to Exhibit&nbsp;10.39 to the Registrant&rsquo;s Registration Annual Report on Form&nbsp;10-K filed on March&nbsp;1, 2021.</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">(10)</TD>
    <TD>Incorporated by reference to Exhibit&nbsp;10.41 to the Registrant&rsquo;s Registration Annual Report on Form&nbsp;10-K filed on March&nbsp;1, 2021.</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">(11)</TD>
    <TD>Incorporated by reference to Exhibit&nbsp;10.42 to the Registrant&rsquo;s Registration Annual Report on Form&nbsp;10-K filed on March&nbsp;1, 2021.</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>(12)</TD>
    <TD>Incorporated by reference to Exhibit&nbsp;10.25 to the Registrant&rsquo;s Registration Annual Report on Form&nbsp;10-K filed on February&nbsp;24, 2022.</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

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<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Item 9. Undertakings.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(a)The undersigned Registrant hereby undertakes:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify">(1)&nbsp;To file, during any period
in which offers or sales are being made, a post-effective amendment to this Registration Statement:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; background-color: white; border-collapse: collapse">
  <TR>
    <TD STYLE="width: 9%; padding-left: 0.5in; text-align: justify">&nbsp;</TD>
    <TD STYLE="vertical-align: top; width: 4%; padding-left: 0.5in; text-align: justify">(i)</TD>
    <TD STYLE="vertical-align: top; padding-left: 0.5in; text-align: justify">To include any prospectus required by Section&nbsp;10(a)(3)&nbsp;of the Securities Act;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; background-color: white; border-collapse: collapse">
  <TR>
    <TD STYLE="width: 9%; padding-left: 0.5in; text-align: justify">&nbsp;</TD>
    <TD STYLE="vertical-align: top; width: 4%; padding-left: 0.5in; text-align: justify">(ii)</TD>
    <TD STYLE="vertical-align: top; padding-left: 0.5in; text-align: justify">To reflect in the prospectus any facts or events arising after the effective date of this Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in this Registration Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule&nbsp;424(b)&nbsp;if, in the aggregate, the changes in volume and price represent no more than 20% change in the maximum aggregate offering price set forth in the &ldquo;Calculation of Registration Fee&rdquo; table in the effective registration statement; and</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; background-color: white; border-collapse: collapse">
  <TR>
    <TD STYLE="width: 9%; padding-left: 0.5in; text-align: justify">&nbsp;</TD>
    <TD STYLE="vertical-align: top; width: 4%; padding-left: 0.5in; text-align: justify">(iii)</TD>
    <TD STYLE="vertical-align: top; padding-left: 0.5in; text-align: justify">To include any material information with respect to the plan of distribution not previously disclosed in this Registration Statement or any material change to such information in this Registration Statement;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify"><I>provided, however</I>, that paragraphs
(a)(1)(i)&nbsp;and (a)(1)(ii)&nbsp;do not apply if the information required to be included in a post-effective amendment by those paragraphs
is contained in periodic reports filed with or furnished to the Commission by the registrant pursuant to Section&nbsp;13 or 15(d)&nbsp;of
the Exchange Act that are incorporated by reference in this Registration Statement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify">(2)&nbsp;That, for the purpose of determining
any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating
to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial&nbsp;<I>bona fide</I>&nbsp;offering
thereof.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify">(3)&nbsp;To remove from registration
by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify">(b)&nbsp;The undersigned registrant
hereby undertakes that, for purposes of determining any liability under the&nbsp;Securities Act, each filing of the registrant&rsquo;s
annual report pursuant to Section&nbsp;13(a)&nbsp;or Section&nbsp;15(d)&nbsp;of the Exchange Act (and, where applicable, each filing of
an employee benefit plan&rsquo;s annual report pursuant to Section&nbsp;15(d)&nbsp;of the Exchange Act) that is incorporated by reference
in this Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial&nbsp;bona fide&nbsp;offering thereof.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify">(c)&nbsp;Insofar as indemnification
for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the registrant pursuant
to the foregoing provisions, or otherwise, the registrant has been advised that in the opinion of the Commission such indemnification
is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification
against such liabilities (other than the payment by the registrant of expenses incurred or paid by a director, officer or controlling
person of the registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling
person in connection with the securities being registered, the registrant will, unless in the opinion of its counsel the matter has been
settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against
public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="sig"></A>SIGNATURES</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Pursuant to the requirements
of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form&nbsp;S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned,
thereunto duly authorized, in the city of Philadelphia, Commonwealth of Pennsylvania, on the 13<SUP>th</SUP> day of June, 2023.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD COLSPAN="3" STYLE="padding: 0.5pt">AMICUS THERAPEUTICS,&nbsp;INC.</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD COLSPAN="3" STYLE="padding: 0.5pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt">By:</TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; padding: 0.5pt 0.5pt 1pt">/s/ Bradley L. Campbell</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 50%; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="width: 3%; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="width: 5%; padding: 0.5pt">Name:</TD>
    <TD STYLE="width: 42%; padding: 0.5pt">Bradley L. Campbell</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt">Title:</TD>
    <TD STYLE="padding: 0.5pt">Chief Executive Officer</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>POWER OF ATTORNEY</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">We, the undersigned officers
and directors of Amicus Therapeutics,&nbsp;Inc., hereby severally constitute and appoint Bradley L. Campbell, John F. Crowley, Daphne
Quimi and Ellen S. Rosenberg, and each of them singly, our true and lawful attorneys with full power to them, and each of them singly,
to sign for us and in our names in the capacities indicated below, the Registration Statement on Form&nbsp;S-8 filed herewith and any
and all subsequent amendments to said Registration Statement, and generally to do all such things in our names and on our behalf in our
capacities as officers and directors to enable Amicus Therapeutics,&nbsp;Inc. to comply with the provisions of the Securities Act of 1933,
as amended, and all requirements of the Securities and Exchange Commission, hereby ratifying and confirming our signatures as they may
be signed by our said attorneys, or any of them, to said Registration Statement and any and all amendments thereto.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Pursuant to the requirements
of the Securities Act of 1933, as amended, this Registration Statement on Form&nbsp;S-8 has been signed by the following persons in the
capacities indicated on the dates indicated.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="width: 34%; border-bottom: black 1pt solid; padding: 0.5pt; text-align: center"><B>Signature</B></TD>
    <TD STYLE="width: 1%; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="width: 32%; border-bottom: black 1pt solid; padding: 0.5pt; text-align: center"><B>Title</B></TD>
    <TD STYLE="width: 1%; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="width: 32%; border-bottom: black 1pt solid; padding: 0.5pt; text-align: center"><B>Date</B></TD></TR>
  <TR>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt 0.5pt 0.25pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1pt solid; padding: 0.5pt">/s/ Bradley L. Campbell</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">President, Chief Executive Officer and Director</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt 0.5pt 0.25pt; text-align: center">June&nbsp;13, 2023</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt 0.5pt 0.25pt">Bradley L. Campbell</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">(Principal Executive Officer)</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-bottom: black 1pt solid; padding: 0.5pt">/s/ Daphne Quimi</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">Chief Financial Officer</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">June&nbsp;13, 2023</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt 0.5pt 0.25pt">Daphne Quimi</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">(Principal Financial Officer and Principal Accounting Officer)</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-bottom: black 1pt solid; padding: 0.5pt">/s/ John F. Crowley</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">Director, Executive Chairman</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">June&nbsp;13, 2023</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt 0.5pt 0.25pt">John F. Crowley</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-bottom: black 1pt solid; padding: 0.5pt">/s/ Lynn D. Bleil</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">Director</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">June&nbsp;13, 2023</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt 0.5pt 0.25pt">Lynn D. Bleil</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-bottom: black 1pt solid; padding: 0.5pt">/s/ Michael A. Kelly</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">Director</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">June&nbsp;13, 2023</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt 0.5pt 0.25pt">Michael A. Kelly</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-bottom: black 1pt solid; padding: 0.5pt">/s/ Margaret G. McGlynn</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">Director</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">June&nbsp;13, 2023</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt 0.5pt 0.25pt">Margaret G. McGlynn</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-bottom: black 1pt solid; padding: 0.5pt">/s/ Michael G. Raab</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">Director</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">June&nbsp;13, 2023</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt 0.5pt 0.25pt">Michael G. Raab</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
</TABLE>

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="margin: 0"></P>

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<P STYLE="margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR>
    <TD STYLE="vertical-align: top; border-bottom: Black 1pt solid; padding: 0.5pt; width: 34%">/s/ Eiry W. Roberts, M.D.</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center; width: 32%">Director</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center; width: 32%">June&nbsp;13, 2023</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt">Eiry W. Roberts, M.D.</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-bottom: black 1pt solid; padding: 0.5pt">/s/ Glenn P. Sblendorio</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">Director</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">June&nbsp;13, 2023</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt 0.5pt 0.25pt">Glenn P. Sblendorio</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-bottom: black 1pt solid; padding: 0.5pt">/s/ Craig A. Wheeler</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">Director</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">June&nbsp;13, 2023</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt 0.5pt 0.25pt">Craig A. Wheeler</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; border-bottom: black 1pt solid; padding: 0.5pt">/s/ Burke W. Whitman</TD>
    <TD STYLE="vertical-align: top; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">Director</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; padding: 0.5pt 0.5pt 0.25pt; text-align: center">June&nbsp;13, 2023</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.5pt 0.5pt 0.25pt">Burke W. Whitman</TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt; text-align: center">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt">&nbsp;</TD>
    <TD STYLE="padding: 0.5pt; text-align: center">&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>tm2318498d1_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
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<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right"><B>Exhibit 5.1</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" BORDER="0" STYLE="width: 100%; margin-top: 0pt; margin-bottom: 0pt; font: 10pt Times New Roman, Times, Serif">
  <TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left; width: 15pc"><P STYLE="margin-top: 0; margin-bottom: 0">Troutman Pepper Hamilton Sanders LLP<BR> 400
Berwyn Park, 899 Cassatt Road&nbsp; <BR> Berwyn, PA 19312-1183</P>
                                              <P STYLE="margin-top: 0; margin-bottom: 0">&nbsp;</P>
                                              <P STYLE="margin-top: 0; margin-bottom: 0">troutman.com</P></TD>
    <TD STYLE="text-align: right"><IMG SRC="tm2318498d1_ex5-1img001.jpg" ALT="">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="border-bottom: Black 1pt solid; text-align: left">&nbsp;</TD>
    <TD STYLE="border-bottom: Black 1pt solid; text-align: right">&nbsp;</TD></TR>
  </TABLE>



<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">June&nbsp;13, 2023</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Amicus Therapeutics,&nbsp;Inc.&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">3675 Market Street&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Philadelphia, PA 19104</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" BORDER="0" STYLE="width: 100%; margin-top: 0pt; margin-bottom: 0pt; font: 10pt Times New Roman, Times, Serif">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 0.25in">&nbsp;</TD>
  <TD STYLE="width: 1in">Re:</TD>
  <TD><U>Registration Statement on Form&nbsp;S-8</U></TD></TR>
</TABLE>


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Ladies and Gentlemen:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in">Reference is made to the
registration statement on Form&nbsp;S-8 (the &ldquo;<B><I>Registration Statement</I></B>&rdquo;) of Amicus Therapeutics,&nbsp;Inc., a
Delaware corporation (the &ldquo;<B><I>Company</I></B>&rdquo;), filed on the date hereof with the Securities and Exchange Commission (the
 &ldquo;<B><I>Commission</I></B>&rdquo;), under the Securities Act of 1933, as amended (the &ldquo;<B><I>Act</I></B>&rdquo;). The Registration
Statement covers (i)&nbsp;an aggregate of 2,850,000 shares (the &ldquo;<B><I>ESPP Shares</I></B>&rdquo;), of the Company&rsquo;s common
stock, par value $0.01 per share (&ldquo;<B><I>Common Stock</I></B>&rdquo;) issuable pursuant to the Company&rsquo;s 2023 Employee Stock
Purchase Plan (the &ldquo;<B><I>ESPP</I></B>&rdquo;) (ii)&nbsp;and 5,000,000 shares (the &ldquo;<B><I>Equity Incentive Plan Shares</I></B>&rdquo;)
of Common Stock issuable pursuant to the Company&rsquo;s Amended and Restated 2007 Equity Incentive Plan (as amended, the &ldquo;<B><I>Equity
Incentive Plan</I></B>&rdquo;).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in">For purposes of this opinion
letter, we have examined the Registration Statement, including the exhibits thereto, the originals or copies, certified or otherwise identified
to our satisfaction, of the Company&rsquo;s Restated Certificate of Incorporation, as amended, the Company&rsquo;s [Second Amended and
Restated By-laws], the ESPP, the Equity Incentive Plan and such other agreements, instruments and documents as we have deemed appropriate
in rendering this opinion.&nbsp; As to matters of fact, we have relied on certain representations of officers of the Company.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in">In our examination of the
aforesaid documents and rendering this opinion, we have assumed the genuineness and authenticity of all signatures on original documents;
the legal capacity of all natural persons; the authenticity of all documents submitted to us as originals; the conformity to originals
of all documents submitted to us as certified or photocopies; the accuracy and completeness of all documents and records reviewed by us;
the accuracy, completeness and authenticity of certificates issued by any governmental official, office or agency and the absence of change
in the information contained therein from the effective date of any such certificate; and the due authorization, execution and delivery
of all documents where authorization, execution and delivery are prerequisites to the effectiveness of such documents.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in">This opinion letter is based
as to matters of law solely on the General Corporation Law of the State of Delaware, as amended. We express no opinion herein as to any
other statutes, rules&nbsp;or regulations. We assume no obligation to supplement this opinion if any applicable law changes after the
date hereof or if we become aware of any fact that might change the opinion expressed herein after the date hereof.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in">Based on, subject to and
limited by the foregoing, we are of the opinion that (A)&nbsp;with respect to the ESPP Shares, following the (i)&nbsp;effectiveness of
the Registration Statement, (ii)&nbsp;issuance of the ESPP Shares in accordance with the terms of the ESPP and (iii)&nbsp;receipt by the
Company of the consideration for the ESPP Shares specified in the applicable resolutions of the Board of Directors or a duly authorized
committee thereof, the ESPP or any underlying award agreements or letters, the ESPP Shares will be validly issued, fully paid and non-assessable;
and (B)&nbsp;with respect to the Equity Incentive Plan Shares, following the (i)&nbsp;effectiveness of the Registration Statement, (ii)&nbsp;issuance
of the Equity Incentive Plan Shares in accordance with the terms of the Equity Incentive Plan and (iii)&nbsp;receipt by the Company of
the consideration for the Equity Incentive Plan Shares specified in the applicable resolutions of the Board of Directors or a duly authorized
committee thereof, the Equity Incentive Plan or any underlying award agreements or letters, the Equity Incentive Plan Shares will be validly
issued, fully paid and non-assessable.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right; text-indent: 0.25in"><IMG SRC="tm2318498d1_ex5-1img002.jpg" ALT="">&nbsp;</P>

<P STYLE="border-bottom: Black 1pt solid; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right; text-indent: 0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in">This opinion letter has been
prepared for use in connection with the Registration Statement. This opinion letter is given as of the date hereof, and we express no
opinion as to the effect of subsequent events or changes in law occurring or becoming effective after the date hereof. We assume no obligation
to update this opinion letter or otherwise advise you with respect to any facts or circumstances or changes in law that may hereafter
occur or come to our attention.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.25in">We hereby consent to the
filing of this opinion as an exhibit to the Registration Statement. In giving such consent, we do not thereby admit that we come within
the category of persons whose consent is required under Section&nbsp;7 of the Act or the rules&nbsp;or regulations of the Commission thereunder.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 50%">&nbsp;</TD>
    <TD STYLE="width: 50%"><FONT STYLE="font-family: Times New Roman, Times, Serif">Very truly yours,</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif">/s/ Troutman Pepper Hamilton Sanders LLP</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&nbsp;</TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif">Troutman Pepper Hamilton Sanders LLP</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"></P>

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</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>tm2318498d1_ex23-1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
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<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right"><B>Exhibit 23.1</B>&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING
FIRM</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We consent to the incorporation by reference in
this Registration Statement (Form S-8) pertaining to the Employee Stock Purchase Plan and Amended and Restated 2007 Equity Incentive Plan
of Amicus Therapeutics, Inc., of our reports dated March 1, 2023, with respect to the consolidated financial statements of Amicus Therapeutics,
Inc., and the effectiveness of internal control over financial reporting of Amicus Therapeutics, Inc., included in its Annual Report (Form
10-K) for the year ended December 31, 2022, filed with the Securities and Exchange Commission.&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">/s/ Ernst &amp; Young LLP</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Iselin, New Jersey</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">June 13, 2023</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

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<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>4
<FILENAME>tm2318498d1_ex-filingfees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right"><B>Exhibit&nbsp;107.1</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Calculation of Filing Fee Table</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><U>Form&nbsp;S-8</U></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(Form&nbsp;Type)</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><U>Amicus Therapeutics,&nbsp;Inc.</U></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(Exact Name of Registrant as Specified in its
Charter)</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><U>Table 1: Newly Registered Securities</U></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="border-bottom: Black 1pt solid; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Security<BR>
Type</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="border-bottom: black 1pt solid; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Security Class&nbsp;Title</FONT></TD>
    <TD>&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Fee<BR>
Calculation<BR>
Rule</FONT></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Amount<BR>
Registered</FONT><FONT STYLE="font-size: 10pt">(1)</FONT></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Proposed<BR>
Maximum<BR>
Offering<BR>
Price Per<BR>
Unit</FONT></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Maximum<BR>
Aggregate Offering<BR>
Price</FONT></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Fee Rate</FONT></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; font-size: 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Amount of<BR>
Registration<BR>
Fee</FONT></TD>
    <TD>&nbsp;</TD></TR>
  <TR STYLE="background-color: rgb(204,238,255)">
    <TD STYLE="vertical-align: top; padding-left: 10pt; font-size: 10pt; text-indent: -10pt; width: 4%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Equity</FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common Stock, $0.01 par value per share, reserved for issuance pursuant to the 2023 Employee Stock Purchase Plan</FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; text-align: right; width: 3%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">457</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; font-size: 10pt; width: 1%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(h)&nbsp;</FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; font-size: 10pt; text-align: right; width: 6%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">2,850,000</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; width: 1%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; text-align: right; width: 6%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">12.47</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; font-size: 10pt; width: 1%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(2)</FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; width: 1%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; text-align: center; width: 6%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">35,539,500</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; text-align: right; width: 6%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">0.0001102</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; width: 1%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; text-align: right; width: 6%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">3,916.45</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; width: 1%">&nbsp;</TD></TR>
  <TR STYLE="background-color: White">
    <TD STYLE="vertical-align: top; padding-left: 10pt; font-size: 10pt; text-indent: -10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Equity</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common Stock, $0.01 par value per share, reserved for issuance pursuant to the Amended and Restated 2007 Equity Incentive Plan</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">457</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(h)&nbsp;</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; font-size: 10pt; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">5,000,000</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">12.47</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(2)</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">62,350,000</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; text-align: justify">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">0.0001102</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">6,870.97</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; font-size: 10pt">&nbsp;</TD></TR>
  <TR STYLE="background-color: rgb(204,238,255)">
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total Offering Amounts</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="text-align: right; vertical-align: bottom; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">7,850,000</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">97,889,500 </FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">10,787.42</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom">&nbsp;</TD></TR>
  <TR STYLE="background-color: White">
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Total Fee Offsets</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom; font-size: 10pt; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&mdash; </FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom">&nbsp;</TD></TR>
  <TR STYLE="background-color: rgb(204,238,255)">
    <TD STYLE="vertical-align: top">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Net Fee Due</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">$</FONT></TD>
    <TD STYLE="vertical-align: bottom; font-size: 10pt; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">10,787.42</FONT></TD>
    <TD STYLE="white-space: nowrap; vertical-align: bottom">&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 4%; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Pursuant to Rule&nbsp;416(a)&nbsp;of the Securities Act of 1933, as amended (the &ldquo;Securities Act&rdquo;), this Registration Statement shall also cover any additional shares of the Registrant&rsquo;s common stock that become issuable under either the 2023 Employee Stock Purchase Plan or the Amended and Restated 2007 Equity Incentive Plan by reason of any stock dividend, stock split, recapitalization or other similar transaction effected without receipt of consideration that increases the number of the Registrant&rsquo;s outstanding shares of common stock. </FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 4%; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(2)</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Estimated in accordance with Rule&nbsp;457(h)(1)&nbsp;under the Securities Act solely for purposes of calculating the registration fee, based on the average of the high and low sales prices for the common stock as reported on the NASDAQ Global Market on June&nbsp;7, 2023. </FONT></TD></TR>
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