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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2023
Income Tax Disclosure [Abstract]  
Schedule of Income (Loss) Before Income Taxes
For financial reporting purposes, income (loss) before income taxes includes the following components:
Years Ended December 31,
(in thousands)202320222021
United States$(234,482)$(343,424)$(333,571)
Foreign84,381 101,385 92,017 
Total$(150,101)$(242,039)$(241,554)
Schedule of Income Tax Expense (Benefit)
Following were the components of income tax expense (benefit) for the years ended December 31, 2023, 2022, and 2021:
Years Ended December 31,
(in thousands)202320222021
Current
Federal$— $— $— 
State14 15 
Foreign6,408 (5,760)8,857 
Deferred
Federal(4,801)274 — 
State(138)34 
Foreign— — — 
Total$1,483 $(5,471)$8,906 
Schedule of Reconciliation of the Statutory Tax Rates and the Effective Tax Rates
A reconciliation of the statutory tax rates and the effective tax rates for the years ended December 31, 2023, 2022, and 2021 are as follows:
Years Ended December 31,
202320222021
Statutory rate(21)%(21)%(21)%
Tax credits(8)(11)(9)
Impact of foreign operations(9)18 
Other
Valuation allowance31 28 
Net%(2)%%
Schedule of Significant Components of the Deferred Tax Assets and Liabilities The significant components of the deferred tax assets and liabilities are as follows:
Years Ended
December 31,
(in thousands)20232022
Deferred tax assets
Intellectual property$— $68,567 
Research tax credit235,532 223,366 
Capitalized research and development costs34,425 29,317 
Net operating loss carry forwards321,004 315,444 
Share-based compensation17,314 16,417 
Interest carry forward limitation17,627 12,558 
Lease liability10,567 11,428 
Inventory1,931 10,400 
Other20,858 20,109 
Gross deferred tax assets659,258 707,606 
Deferred tax liabilities
Royalty payable— (68,567)
Other(10,004)(11,745)
Total net deferred tax assets649,254 627,294 
Less: valuation allowance(649,254)(632,233)
Net deferred tax liability$— $(4,939)