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Summary of Significant Accounting Policies - Revenue by Product and Geographical Area (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Disaggregation of Revenue [Line Items]      
Net product sales $ 399,356 $ 329,233 $ 305,514
Galafold      
Disaggregation of Revenue [Line Items]      
Net product sales 387,777 329,046 305,514
Pombiliti + Opfolda      
Disaggregation of Revenue [Line Items]      
Net product sales 11,579 187 0
U.S.      
Disaggregation of Revenue [Line Items]      
Net product sales 146,937 115,946 95,387
Ex-U.S.      
Disaggregation of Revenue [Line Items]      
Net product sales $ 252,419 $ 213,287 $ 210,127