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Consolidated Statements of Operations - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Income Statement [Abstract]      
Net product sales $ 399,356 $ 329,233 $ 305,514
Cost of goods sold 37,326 38,599 34,466
Gross profit 362,030 290,634 271,048
Operating expenses:      
Research and development 152,381 276,677 272,049
Selling, general, and administrative 275,270 213,041 192,710
Changes in fair value of contingent consideration payable 2,583 1,078 6,514
Loss on impairment of assets 1,134 6,616 0
Depreciation and amortization 7,873 5,342 6,209
Total operating expenses 439,241 502,754 477,482
Loss from operations (77,211) (212,120) (206,434)
Other (expense) income:      
Interest income 7,078 3,024 509
Interest expense (50,149) (37,119) (32,471)
Loss on extinguishment of debt (13,933) 0 (257)
Other (expense) income (15,886) 4,176 (2,901)
Loss before income tax (150,101) (242,039) (241,554)
Income tax (expense) benefit (1,483) 5,471 (8,906)
Net loss attributable to common stockholders $ (151,584) $ (236,568) $ (250,460)
Net loss attributable to common stockholders per common share - basic (in dollars per share) $ (0.51) $ (0.82) $ (0.92)
Net loss attributable to common stockholders per common share - diluted (in dollars per share) $ (0.51) $ (0.82) $ (0.92)
Weighted-average common shares outstanding - basic (in shares) 295,164,515 289,057,198 271,421,986
Weighted-average common shares outstanding - diluted (in shares) 295,164,515 289,057,198 271,421,986