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Cover - USD ($)
 12 Months Ended
Dec. 31, 2023
Feb. 13, 2024
Jun. 30, 2023
Cover [Abstract]      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2023    
Current Fiscal Year End Date --12-31    
Document Transition Report false    
Entity File Number 001-33497    
Entity Registrant Name Amicus Therapeutics, Inc.    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 71-0869350    
Entity Address, Address Line One 47 Hulfish Street    
Entity Address, City or Town Princeton    
Entity Address, State or Province NJ    
Entity Address, Postal Zip Code 08542    
City Area Code (609)    
Local Phone Number 662-2000    
Title of 12(b) Security Common Stock, par value $0.01 per share    
Trading Symbol FOLD    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer Yes    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Large Accelerated Filer    
Entity Small Business false    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag true    
Document Financial Statement Error Correction false    
Entity Shell Company false    
Entity Public Float     $ 3,556,948,517
Entity Common Stock, Shares Outstanding   295,382,614  
Documents Incorporated by Reference Portions of the Proxy Statement for the registrant's 2024 Annual Meeting of Stockholders which is to be filed subsequent to the date hereof are incorporated by reference into Part III of this Annual Report on Form 10-K.    
Entity Central Index Key 0001178879    
Amendment Flag false    
Document Fiscal Year Focus 2023    
Document Fiscal Period Focus FY