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v3.25.0.1

Income Taxes - Deferred and Valuation Allowance (Details) - USD ($) $ in Thousands | Dec. 31, 2024 | Dec. 31, 2023
--- | --- | ---
Deferred tax assets |  |
Net operating loss carry forwards | $ 302,066 | $ 321,004
Research tax credit | 234,189 | 235,532
Capitalized research and development costs | 34,883 | 34,425
Share-based compensation | 20,045 | 17,314
Lease liability | 10,026 | 10,567
Interest carry forward limitation | 9,097 | 17,627
Inventory | 1,599 | 1,931
Other | 5,267 | 20,858
Gross deferred tax assets | 617,172 | 659,258
Deferred tax liabilities |  |
Other | (8,042) | (10,004)
Total net deferred tax assets | 609,130 | 649,254
Less: valuation allowance | (609,130) | (649,254)
Net deferred tax liability | $ 0 | $ 0

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