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Summary of Significant Accounting Policies - Revenue by Product and Geographical Area (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024
Disaggregation of Revenue [Line Items]
Net product sales	$ 125,249	$ 110,403
Galafold
Disaggregation of Revenue [Line Items]
Net product sales	104,244	99,359
Pombiliti + Opfolda
Disaggregation of Revenue [Line Items]
Net product sales	21,005	11,044
UNITED STATES | Galafold
Disaggregation of Revenue [Line Items]
Net product sales	40,166	34,115
UNITED STATES | Pombiliti + Opfolda
Disaggregation of Revenue [Line Items]
Net product sales	9,827	3,260
Non-US | Galafold
Disaggregation of Revenue [Line Items]
Net product sales	64,078	65,244
Non-US | Pombiliti + Opfolda
Disaggregation of Revenue [Line Items]
Net product sales	$ 11,178	$ 7,784

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