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Summary of Significant Accounting Policies - Revenue by Product and Geographical Area (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024
Disaggregation of Revenue [Line Items]
Net product sales	$ 169,061	$ 141,517	$ 448,998	$ 378,589
Galafold
Disaggregation of Revenue [Line Items]
Net product sales	138,347	120,381	371,463	330,557
Pombiliti + Opfolda
Disaggregation of Revenue [Line Items]
Net product sales	30,714	21,136	77,535	48,032
United States | Galafold
Disaggregation of Revenue [Line Items]
Net product sales	57,198	47,333	150,964	124,218
United States | Pombiliti + Opfolda
Disaggregation of Revenue [Line Items]
Net product sales	13,070	8,859	33,627	19,487
Non-US | Galafold
Disaggregation of Revenue [Line Items]
Net product sales	81,149	73,048	220,499	206,339
Non-US | Pombiliti + Opfolda
Disaggregation of Revenue [Line Items]
Net product sales	$ 17,644	$ 12,277	$ 43,908	$ 28,545

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