XML 34 R35.htm IDEA: XBRL DOCUMENT v3.3.0.814
Commitment and Contingencies - Additional Information (Detail)
 1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Sep. 30, 2015
USD ($)
$ / shares
shares
Jul. 31, 2015
USD ($)
Jul. 08, 2015
USD ($)
Jun. 30, 2015
USD ($)
ft²
Dec. 31, 2014
USD ($)
shares
Mar. 31, 2014
USD ($)
shares
Sep. 30, 2015
USD ($)
$ / shares
shares
Sep. 30, 2014
USD ($)
Sep. 30, 2015
USD ($)
$ / shares
shares
Sep. 30, 2014
USD ($)
Dec. 31, 2014
USD ($)
Apr. 30, 2014
USD ($)
Loss Contingencies [Line Items]                            
Lease Expiration Date                     Aug. 31, 2016      
Number of square foot of facility leased. | ft²           44,681                
Extended lease term                     7 years      
Base rent                     $ 179,000      
Percentage of annual increase of base rent                     3.00%      
Rent expense                 $ 667,000 $ 59,000 $ 825,000 $ 158,000    
Research and development                 3,950,000 328,000 6,328,000 691,000    
Issuance of common stock                     77,975,000      
Consideration for the sale of the licensed patents                     $ 75,000      
Notes payable                           $ 1,000,000
Ownership interest of the total outstanding common shares                     7.00%      
Warrant exercise term                     10 years      
Class of warrant or right outstanding number of shares exercised | shares                     37,030      
Proceeds from issuance of common stock net of issuance costs         $ 7,000,000 $ 70,976,000   $ 3,000,000            
Percentage of equity owned by partners               7.00%            
Expense earned or paid     $ 0           6,000 6,000 $ 19,000 44,000    
Milestone payments                     $ 0 0    
License agreement termination notice period                     60 days      
Fox Chase Cancer Center License Agreement                            
Loss Contingencies [Line Items]                            
Expense earned or paid                 $ 0 $ 29,000 $ 51,000 $ 149,000    
Rush University Medical Center License Agreement                            
Loss Contingencies [Line Items]                            
Consideration for the sale of the licensed patents                         $ 250,000,000  
Period of license agreement                         12 years  
Minimum annual royalty payment                         $ 25,000  
Payments in license agreement                         $ 2,500,000  
Common Class A                            
Loss Contingencies [Line Items]                            
Exchanged warrants, in share | shares     123,433           123,433   123,433      
Stock price of warrants | $ / shares     $ 2.44           $ 2.44   $ 2.44      
Warrants exchange to purchase common stock | shares               156,109            
Purchase of fully-vested incentive stock option | shares               740,600            
Private Placement One                            
Loss Contingencies [Line Items]                            
Proceeds from issuance of common stock net of issuance costs       $ 17,000,000                    
Private Placement One | Sorrento | Common Class A                            
Loss Contingencies [Line Items]                            
Issuance of common stock, Shares | shares             4,557,537       4,557,537      
Proceeds from issuance of common stock gross of issuance costs             $ 8,000,000       $ 8,000,000      
Private Placement Two | Common Class A                            
Loss Contingencies [Line Items]                            
Issuance of common stock, Shares | shares             26,252,262              
Proceeds from issuance of common stock gross of issuance costs             $ 49,495,000              
Private Placement Two | Sorrento | Common Class A                            
Loss Contingencies [Line Items]                            
Issuance of common stock, Shares | shares             1,060,789       1,060,789      
Issuance of common stock             $ 2,000,000       $ 2,000,000      
2013 Securities Purchase Agreement                            
Loss Contingencies [Line Items]                            
Notes payable     $ 1,000,000           $ 1,000,000   1,000,000      
2013 Securities Purchase Agreement | Common Class A                            
Loss Contingencies [Line Items]                            
Notes payable     $ 950,000           $ 950,000   950,000      
Scenario Forecast                            
Loss Contingencies [Line Items]                            
Research and development $ 2,000,000 $ 2,000,000                        
Sub Lease Agreements                            
Loss Contingencies [Line Items]                            
Rent expense                     $ 0