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Condensed Consolidated Statements of Operations (Unaudited) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2018	Mar. 31, 2017
Income Statement [Abstract]
Revenue	$ 5	$ 11
Operating expenses:
Research and development (including amounts to related parties)	13,991	9,248
Selling, general and administrative (including amounts to related parties)	14,298	16,227
Total operating expenses	28,289	25,475
Loss from operations	(28,284)	(25,464)
Other income:
Investment income, net	505	779
Interest expense (including amounts to related parties)	(33)	(37)
Other income, net (including amounts to related parties)	169	109
Total other income	641	851
Loss before income taxes	(27,643)	(24,613)
Income tax benefit	(124)	(98)
Net loss	$ (27,519)	$ (24,515)
Net loss per share:
Basic and diluted	$ (0.35)	$ (0.30)
Weighted average number of shares during the period:
Basic and diluted	79,036,614	82,138,438

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