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Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Jun. 30, 2019
Accounting Policies [Line Items]      
Revenues $ 605 $ 2,202  
Operating expenses 221,485 158,453  
Assets 221,381 269,786  
Liabilities $ 339,871 253,460  
Disposition of investment in non-controlling interests   $ 18,353  
Precision Biologics      
Accounting Policies [Line Items]      
Percentage of ownership interest     68.50%
Globe Immune      
Accounting Policies [Line Items]      
Percentage of ownership interest 69.10% 60.00%  
Globe Immune | VIE      
Accounting Policies [Line Items]      
Debt Instrument, interest rate 5.00%    
Debt Instrument, face amount $ 6,000    
Payments for advance to affiliate 0 $ 1,200  
Revenues 0 200  
Operating expenses 2,000 7,700  
Assets 500 2,300  
Liabilities $ 300 $ 1,500