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Financial Statement Details (Tables)

12 Months Ended

Dec. 31, 2023

Financial Statement Details [Abstract]

Schedule of Prepaid Expenses and Other Current Assets

Prepaid expenses and other current assets consist of the following (in thousands):

			As of December 31,
			2023						2022
Prepaid research and development costs			$	7,847					$	11,704
Prepaid services			5,869						8,013
Prepaid insurance			2,242						2,282
Prepaid software license fees			2,100						2,195
Insurance premium financing asset			1,475						1,417
Insurance claims receivable			1,149						—
Prepaid equipment maintenance			1,183						833
ERP system implementation cost			1,087						920
Prepaid supplies			—						2,160
Other			2,651						1,979
Prepaid expenses and other current assets			$	25,603					$	31,503

Schedule of Property, Plant and Equipment, Net

Depreciation of property, plant and equipment is calculated using the straight-line method over the estimated useful lives of the assets, as follows:

Buildings						39 years
Software						3 years
Laboratory equipment						5 to 7 years
Furniture & fixtures						5 years
IT equipment						3 years
Leasehold improvements						The lesser of the lease term or life of the asset

Property, plant and equipment, net, consist of the following (in thousands):

			As of December 31,
			2023						2022
Leasehold improvements			$	72,552					$	68,710
Equipment			69,915						67,945
Construction in progress			84,436						72,693
Software			1,666						1,657
Furniture & fixtures			1,889						1,906
Gross property, plant and equipment			230,458						212,911
Less: Accumulated depreciation and amortization			84,376						69,252
Property, plant and equipment, net			$	146,082					$	143,659

Schedule of Intangible Assets, Net

The gross carrying amounts and accumulated amortization of intangible assets are as follows at the dates indicated (in thousands):

			December 31, 2023
			Weighted- Average Life (in years)						Gross Carrying Amount						Accumulated Amortization						Impairment						Net Carrying Amount
Definite-lived: Favorable leasehold rights			8.1						$	20,398					$	(3,825)					$	—					$	16,573
Indefinite-lived: IPR&D									1,406						—						(886)						520
Total intangible assets									$	21,804					$	(3,825)					$	(886)					$	17,093

			December 31, 2022
			Weighted- Average Life (in years)						Gross Carrying Amount						Accumulated Amortization						Impairment						Net Carrying Amount
Favorable leasehold rights			9.1						$	20,398					$	(1,785)					$	—					$	18,613
Organized workforce									831						(150)						(681)						—
Total definite-lived intangible assets									21,229						(1,935)						(681)						18,613
Indefinite-lived: IPR&D									1,390						—						—						1,390
Total intangible assets									$	22,619					$	(1,935)					$	(681)					$	20,003

Schedule of Finite-Lived Intangible Assets, Future Amortization Expense

Future amortization expense associated with our definite-lived intangible assets is as follows (in thousands):

Years ending December 31:						Definite-lived Intangible Assets
2024						$	2,040
2025						2,040
2026						2,040
2027						2,040
2028						2,040
Thereafter						6,373
Total						$	16,573

Schedule of Accrued Expenses and Other Liabilities

Accrued expenses and other liabilities consist of the following (in thousands):

			As of December 31,
			2023						2022
Accrued bonus			$	11,350					$	12,068
Accrued professional and service fees			9,829						6,685
Accrued research and development costs			7,700						1,930
Accrued compensation			6,241						6,040
Accrued preclinical and clinical trial costs			4,218						4,985
Financing obligation – current portion			1,475						1,417
Accrued construction costs			1,179						7,072
Other			716						1,628
Accrued expenses and other liabilities			$	42,708					$	41,825

Schedule of Interest and Investment (Loss) Income, Net

Interest and investment income (loss), net consists of the following (in thousands):

			Year Ended December 31,
			2023						2022						2021
Unrealized losses from equity securities			$	(1,591)					$	(4,190)					$	(4,615)
Interest income			863						2,708						836
Investment accretion income (amortization expense), net			1,844						(1,486)						(488)
Net realized gains (losses) on investments			15						(122)						167
Interest and investment income (loss), net			$	1,131					$	(3,090)					$	(4,100)

Schedule of Interest Expense

Interest expense consists of the following (in thousands):

			Year Ended December 31,
			2023						2022						2021
Interest expense on related-party notes payable			$	86,453					$	47,145					$	14,695
Amortization of related-party notes discounts			42,396						16,282						62
Other interest expense			349						88						92
Interest expense			$	129,198					$	63,515					$	14,849

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