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Leases - Additional Information (Details) $ in Thousands | 1 Months Ended | 3 Months Ended | 6 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | ---
Aug. 31, 2020 USD ($) ft² Option | Apr. 30, 2020 USD ($) Option | Mar. 31, 2020 USD ($) | Jul. 31, 2019 | Jun. 30, 2019 | Apr. 30, 2019 USD ($) Option | Oct. 31, 2018 | Feb. 28, 2018 USD ($) ft² | Jun. 30, 2021 USD ($) | Jun. 30, 2021 USD ($) | Jun. 30, 2020 USD ($) | Jan. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | Oct. 31, 2020 USD ($)
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Operating lease, option to extend |  |  |  |  |  |  |  |  |  | option to extend the lease for two terms of five years each, which are not reasonably certain of exercise. |  |  |  |
Operating lease right-of-use assets |  |  |  |  |  |  |  |  | $ 105,315 | $ 105,315 |  |  | $ 86,859 |
Lease liability |  |  |  |  |  |  |  |  | $ 136,284 | 136,284 |  |  |  |
Increase in operating lease liability |  |  |  |  |  |  |  |  |  | $ 11,888 | $ (1,801) |  |  |
Office and Laboratory Space |  |  |  |  |  |  |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Square feet of office and laboratory space | ft² |  |  |  |  |  |  |  | 38,203 |  |  |  |  |  |
Operating lease, commencement month and year |  |  |  | 2019-10 | 2019-10 |  |  | 2018-03 |  |  |  |  |  |
Operating lease, termination month and year |  |  |  | 2021-12 | 2021-12 |  |  | 2028-09 |  |  |  |  |  |
Operating lease, existence of option to extend |  |  |  |  |  | true |  |  |  |  |  |  |  |
Operating lease, number of renewal options | Option |  |  |  |  |  | 2 |  |  |  |  |  |  |  |
Operating lease, option to extend term |  |  |  |  |  | 5 years |  |  |  |  |  |  |  |
Leasehold improvements landlord allowance |  |  |  |  |  | $ 23,400 |  | $ 6,100 |  |  |  |  |  |
Operating lease, termination date |  |  |  |  |  |  |  |  | Feb. 28, 2034 |  |  |  |  |
Increase in operating lease right-of-use assets |  |  |  |  |  |  |  |  | $ 500 |  |  |  |  |
Increase in operating lease liability |  |  |  |  |  |  |  |  | $ 500 |  |  |  |  |
Operating lease term |  |  |  |  |  |  |  |  | 12 years | 12 years |  |  |  |
Office and Laboratory Space | Letter of Credit |  |  |  |  |  |  |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Lessee, operating lease, security deposit |  |  |  |  |  | $ 11,800 |  |  |  |  |  |  |  |
Office and Laboratory Space | First Phase of Lease in October 2020 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Operating lease, commencement month and year |  |  |  |  |  | 2020-10 |  |  |  |  |  |  |  |
Operating lease right-of-use assets |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 66,800
Lease liability |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 68,800
Office and Laboratory Space | Second Phase of Lease in January 2021 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Operating lease, commencement month and year |  |  |  |  |  | 2021-01 |  |  |  |  |  |  |  |
Operating lease right-of-use assets |  |  |  |  |  |  |  |  |  |  |  | $ 22,000 |  |
Lease liability |  |  |  |  |  |  |  |  |  |  |  | $ 23,000 |  |
Laboratory Space |  |  |  |  |  |  |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Operating lease, commencement month and year |  | 2020-04 |  |  |  |  | 2019-04 |  |  |  |  |  |  |
Operating lease, termination month and year |  | 2025-12 |  |  |  |  |  |  |  |  |  |  |  |
Operating lease, amendment month and year |  | 2020-04 | 2020-03 |  |  |  |  |  |  |  |  |  |  |
Operating lease, option to extend |  | The amended lease is subject to fixed-rate rent escalations and provides an option to extend the lease for two additional two-year periods through December 31, 2029, which are not reasonably certain of being exercised. |  |  |  |  |  |  |  |  |  |  |  |
Operating lease, existence of option to extend |  | true |  |  |  |  |  |  |  |  |  |  |  |
Operating lease, number of renewal options | Option |  | 2 |  |  |  |  |  |  |  |  |  |  |  |
Operating lease, option to extend term |  | 2 years |  |  |  |  |  |  |  |  |  |  |  |
Operating lease right-of-use assets |  | $ 1,800 | $ 4,200 |  |  |  |  |  |  |  |  |  |  |
Lease liability |  | $ 1,800 | $ 4,200 |  |  |  |  |  |  |  |  |  |  |
Manufacturing Facility | Alexandria Real Estate Equities, Inc. |  |  |  |  |  |  |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Operating lease, existence of option to extend | true |  |  |  |  |  |  |  |  |  |  |  |  |
Operating lease, number of renewal options | Option | 2 |  |  |  |  |  |  |  |  |  |  |  |  |
Operating lease, option to extend term | 5 years |  |  |  |  |  |  |  |  |  |  |  |  |
Manufacturing facility, number of square feet | ft² | 100,000 |  |  |  |  |  |  |  |  |  |  |  |  |
Operating lease term | 15 years |  |  |  |  |  |  |  |  |  |  |  |  |
Lessee operating lease, description |  |  |  |  |  |  |  |  |  | The lease has a term of 15 years following the commencement date and provides the Company the option to extend the lease term for two five-year terms. It is subject to fixed rate escalation increases and also provides up to $20.0 million for reimbursement of tenant improvements. As the lease had not commenced as of June 30, 2021, the Company has not recorded an operating lease ROU asset or lease liability for this lease in the accompanying condensed consolidated balance sheets. |  |  |  |
Lessee, operating lease, lease not yet commenced anticipated undiscounted lease payments due | $ 63,900 |  |  |  |  |  |  |  |  |  |  |  |  |
Anticipated period for leasehold improvements | 5 years |  |  |  |  |  |  |  |  |  |  |  |  |
Manufacturing Facility | Alexandria Real Estate Equities, Inc. | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Leasehold improvements landlord allowance | $ 20,000 |  |  |  |  |  |  |  |  |  |  |  |  |
Anticipated leasehold improvement amount | $ 83,000 |  |  |  |  |  |  |  |  |  |  |  |  |

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