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Preferred and Common Stock - Additional Information (Details) - USD ($) |  | 1 Months Ended | 3 Months Ended | 4 Months Ended | 6 Months Ended |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Jan. 16, 2021 | Aug. 03, 2021 | Jul. 31, 2021 | Jun. 30, 2021 | Apr. 30, 2021 | Oct. 31, 2020 | Feb. 29, 2020 | Jun. 30, 2021 | Mar. 31, 2021 | Mar. 31, 2020 | Jul. 31, 2021 | Jun. 30, 2021 | Jul. 07, 2021 | May 10, 2021 | Dec. 31, 2020 | Jan. 31, 2020
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock, shares authorized |  |  |  | 25,000,000 |  |  |  | 25,000,000 |  |  |  | 25,000,000 |  |  | 25,000,000 | 25,000,000
Preferred stock, par value per share |  |  |  | $ 0.01 |  |  |  | $ 0.01 |  |  |  | $ 0.01 |  |  | $ 0.01 | $ 0.01
Common stock, shares authorized |  |  |  | 250,000,000 |  |  |  | 250,000,000 |  |  |  | 250,000,000 |  |  | 250,000,000 | 250,000,000
Common stock, par or stated value per share |  |  |  | $ 0.01 |  |  |  | $ 0.01 |  |  |  | $ 0.01 |  |  | $ 0.01 | $ 0.01
Gross proceeds from issuance of common stock |  |  |  |  |  | $ 135,100,000 |  |  |  |  |  |  |  |  |  |
Common stock, voting rights |  |  |  |  |  |  |  |  |  |  |  | The holders of the Company’s common stock are entitled to one vote for each share of common stock. |  |  |  |
Common Stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued and sold |  |  |  |  |  | 5,750,000 |  | 1,761,285 | 2,795,700 | 12,176,471 |  |  |  |  |  |
Public offering price per share |  |  |  |  |  | $ 23.50 |  |  |  |  |  |  |  |  |  |
Net proceeds from sale of common stock |  |  |  |  |  | $ 126,600,000 | $ 188,300,000 |  |  |  |  |  |  |  |  |
Issuance of common stock for success payment liability, Shares |  |  |  |  |  |  |  | 349,650 |  |  |  |  |  |  |  |
Prime Medicine Inc | Common Stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued and sold |  |  |  |  |  | 200,307 |  |  |  |  |  |  |  |  |  |
Broad Institute |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock for success payment liability, Shares |  |  |  | 174,825 |  |  |  |  |  |  |  |  |  |  |  |
Success payments liability |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 15,000,000.0 |  |
Harvard Institute |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock for success payment liability, Shares |  |  |  | 174,825 |  |  |  |  |  |  |  |  |  |  |  |
Success payments liability |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 15,000,000.0 |  |
Jeffries LLC Amended Sales Agreement | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Gross proceeds from issuance of common stock |  | $ 11,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Jeffries LLC Amended Sales Agreement | Common Stock | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued and sold |  | 108,617 |  |  |  |  |  |  |  |  |  |  |  |  |  |
IPO | Common Stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued and sold |  |  |  |  |  |  | 12,176,471 |  |  |  |  |  |  |  |  |
Public offering price per share |  |  |  |  |  |  | $ 17.00 |  |  |  |  |  |  |  |  |
Gross proceeds from issuance of common stock |  |  |  |  |  |  | $ 207,000,000.0 |  |  |  |  |  |  |  |  |
Net proceeds from sale of common stock |  |  |  |  |  |  | $ 188,300,000 |  |  |  |  |  |  |  |  |
Shares issued upon conversion of preferred stock |  |  |  |  |  |  | 29,127,523 |  |  |  |  |  |  |  |  |
Underwriters Option | Common Stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued and sold |  |  |  |  |  | 750,000 | 1,588,235 |  |  |  |  |  |  |  |  |
Private Placement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Gross proceeds from issuance of common stock | $ 260,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Private Placement | Common Stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued and sold | 2,795,700 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Public offering price per share | $ 93.00 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Net proceeds from sale of common stock | $ 252,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
At-The-Market | Jeffries LLC Amended Sales Agreement | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued and sold |  | 108,617 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Gross proceeds from issuance of common stock |  | $ 11,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Aggregate gross proceeds of shares authorized under ATM sales agreement |  |  |  |  |  |  |  |  |  |  |  |  | $ 500,000,000.0 |  |  |
At-The-Market | Jeffries LLC Sales Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Gross proceeds from sale of common stock |  |  |  |  |  |  |  |  |  |  |  | $ 300,000,000.0 |  |  |  |
Stock sold during period shares, new issues |  |  |  |  |  |  |  |  |  |  |  | 2,908,009 |  |  |  |
Shares issued and sold |  |  |  | 1,761,285 |  |  |  |  |  |  |  |  |  |  |  |
Public offering price per share |  |  |  | $ 103.16 |  |  |  | $ 103.16 |  |  |  | $ 103.16 |  |  |  |
Gross proceeds from issuance of common stock |  |  |  | $ 163,200,000 |  |  |  |  |  |  |  |  |  |  |  |
At-The-Market | Jeffries LLC Sales Agreement | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Aggregate gross proceeds of shares authorized under ATM sales agreement |  |  |  |  | $ 300,000,000.0 |  |  |  |  |  |  |  |  |  |  |
Commission rate |  |  |  |  | 3.00% |  |  |  |  |  |  |  |  |  |  |
At-The-Market | Jeffries LLC Sales Agreement | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued and sold |  |  | 1,146,724 |  |  |  |  |  |  |  |  |  |  |  |  |
Gross proceeds from issuance of common stock |  |  | $ 136,800,000 |  |  |  |  |  |  |  |  |  |  |  |  |
Net proceeds from sale of common stock |  |  |  |  |  |  |  |  |  |  | $ 290,500,000 |  |  |  |  |

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