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Fair Value of Financial Instruments - Additional Information (Details) - USD ($) $ in Thousands | 1 Months Ended | 3 Months Ended | 6 Months Ended |  |
--- | --- | --- | --- | --- | ---
Feb. 29, 2020 | Jun. 30, 2021 | Jun. 30, 2020 | Jun. 30, 2021 | Jun. 30, 2020 | Feb. 23, 2021 | Dec. 31, 2020
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |
Fair value contingent liabilities |  | $ 37,559 |  | $ 37,559 |  |  | $ 0
Equity securities recognition amount |  | 25,814 | $ 517 | 26,852 | $ 517 |  |
Verve Therapeutics, Inc. |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |
Equity securities recognition amount |  | 25,800 |  | 26,900 |  |  |
Equity securities |  | 29,300 |  | 29,300 |  |  |
Verve Therapeutics, Inc. | Common Stock |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |
Number of shares purchased under equity method | 546,970 |  |  |  |  |  |
Guide Therapeutics, Inc. | Merger Agreement |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |
Fair value contingent liabilities |  | $ 37,600 |  | $ 37,600 |  | $ 36,500 |
Technology Milestones | Guide Therapeutics, Inc. | Maximum | Merger Agreement | Former Stockholders and Optionholders |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |
Potential milestone payable in form of common stock |  |  |  |  |  | 100,000 |
Product Milestones | Guide Therapeutics, Inc. | Maximum | Merger Agreement | Former Stockholders and Optionholders |  |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |  |
Potential milestone payable in form of common stock |  |  |  |  |  | $ 220,000 |

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