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v3.21.2

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2021 | Jun. 30, 2020
Operating activities |  |
Net loss | $ (277,813) | $ (64,676)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 3,067 | 2,245
Amortization of investment discount (premiums) | (3) | (104)
In-process research and development charge | 154,953 |
Stock-based compensation expense | 15,100 | 5,561
Change in operating lease right-of-use assets | 4,634 | 1,985
Non-cash research and development license expense, net | 0 | 264
Change in fair value of derivative liabilities | 44,200 | 11,400
Change in fair value of contingent consideration liabilities | 1,046 |
Change in fair value of non-controlling equity investments | (26,852) | (517)
Other | 63 |
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | (3,106) | (4,215)
Collaboration receivable | (50,000) |
Other long-term assets | (197) | (68)
Accounts payable | 382 | (53)
Accrued expenses and other liabilities | 1,647 | (239)
Operating lease liabilities | 11,888 | (1,801)
Deferred revenue | 49,988 | (12)
Other long-term liabilities | (102) |
Net cash used in operating activities | (71,105) | (50,230)
Investing activities |  |
Purchases of property and equipment | (27,662) | (5,413)
Purchases of marketable securities | (428,246) | (135,959)
Maturities of marketable securities | 162,525 | 88,198
Net cash acquired from Guide | 620 |
Purchase of long-term investment | 0 | (750)
Net cash used in investing activities | (292,763) | (53,924)
Financing activities |  |
Proceeds from initial public offering, net of underwriting discount | 0 | 192,510
Proceeds from issuance of common shares, net of commissions | 418,282 |
Payment of equity offering costs | (8,479) | (1,665)
Proceeds from equipment financings |  | 1,625
Repayment of equipment financings | (1,046) | (747)
Proceeds from exercise of stock options | 4,955 | 512
Net cash provided by financing activities | 413,712 | 192,235
Net change in cash, cash equivalents and restricted cash | 49,844 | 88,081
Cash, cash equivalents and restricted cash—beginning of period | 177,011 | 50,553
Cash, cash equivalents and restricted cash—end of period | 226,855 | 138,634
Supplemental disclosure of cash flow information: |  |
Cash paid for interest | 307 | 282
Supplemental disclosure of noncash investing and financing activities: |  |
Conversion of redeemable convertible preferred stock to common stock upon closing of the initial public offering |  | 303,326
Property and equipment additions in accounts payable and accrued expenses | 4,430 | 747
Operating lease liabilities arising from obtaining right-of-use assets | 24,164 | 5,795
Fair value of common shares issued to settle success payment liability | 30,000 |
Contingent consideration liabilities assumed in asset acquisition | 36,513 |
Fair value of equity instruments issued in connection with asset acquisition | $ 120,032 |
Accretion of redeemable convertible preferred stock to redemption value, including dividends on preferred stock |  | $ 1,277

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