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Nature of the Business and Basis of Presentation - Additional Information (Details) - USD ($) |  |  | 1 Months Ended | 3 Months Ended | 4 Months Ended | 6 Months Ended |  |
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Feb. 23, 2021 | Jan. 16, 2021 | Aug. 03, 2021 | Jul. 31, 2021 | Jun. 30, 2021 | Apr. 30, 2021 | Feb. 28, 2021 | Oct. 31, 2020 | Feb. 29, 2020 | Jun. 30, 2021 | Mar. 31, 2021 | Mar. 31, 2020 | Jul. 31, 2021 | Jun. 30, 2021 | Jul. 07, 2021 | Dec. 31, 2020
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Gross proceeds from issuance of common stock |  |  |  |  |  |  |  | $ 135,100,000 |  |  |  |  |  |  |  |
Accumulated deficit |  |  |  |  | $ 675,449,000 |  |  |  |  | $ 675,449,000 |  |  |  | $ 675,449,000 |  | $ 397,636,000
Cash, cash equivalents, and marketable securities |  |  |  |  | $ 615,300,000 |  |  |  |  | $ 615,300,000 |  |  |  | $ 615,300,000 |  |
Common Stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued and sold |  |  |  |  |  |  |  | 5,750,000 |  | 1,761,285 | 2,795,700 | 12,176,471 |  |  |  |
Public offering price per share |  |  |  |  |  |  |  | $ 23.50 |  |  |  |  |  |  |  |
Net proceeds from sale of common stock |  |  |  |  |  |  |  | $ 126,600,000 | $ 188,300,000 |  |  |  |  |  |  |
IPO | Common Stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued and sold |  |  |  |  |  |  |  |  | 12,176,471 |  |  |  |  |  |  |
Public offering price per share |  |  |  |  |  |  |  |  | $ 17.00 |  |  |  |  |  |  |
Gross proceeds from issuance of common stock |  |  |  |  |  |  |  |  | $ 207,000,000.0 |  |  |  |  |  |  |
Net proceeds from sale of common stock |  |  |  |  |  |  |  |  | $ 188,300,000 |  |  |  |  |  |  |
Shares issued upon conversion of preferred stock |  |  |  |  |  |  |  |  | 29,127,523 |  |  |  |  |  |  |
Underwriters Option | Common Stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued and sold |  |  |  |  |  |  |  | 750,000 | 1,588,235 |  |  |  |  |  |  |
Private Placement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Gross proceeds from issuance of common stock |  | $ 260,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Private Placement | Common Stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued and sold |  | 2,795,700 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Public offering price per share |  | $ 93.00 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Net proceeds from sale of common stock |  | $ 252,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Jeffries LLC Amended Sales Agreement | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Gross proceeds from issuance of common stock |  |  | $ 11,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |
Jeffries LLC Amended Sales Agreement | Common Stock | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued and sold |  |  | 108,617 |  |  |  |  |  |  |  |  |  |  |  |  |
Jeffries LLC Amended Sales Agreement | At-The-Market | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued and sold |  |  | 108,617 |  |  |  |  |  |  |  |  |  |  |  |  |
Aggregate gross proceeds of shares authorized under ATM sales agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 500,000,000.0 |
Gross proceeds from issuance of common stock |  |  | $ 11,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |
Jeffries LLC Sales Agreement | At-The-Market |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock sold during period shares, new issues |  |  |  |  |  |  |  |  |  |  |  |  |  | 2,908,009 |  |
Gross proceeds from sale of common stock |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 300,000,000.0 |  |
Shares issued and sold |  |  |  |  | 1,761,285 |  |  |  |  |  |  |  |  |  |  |
Public offering price per share |  |  |  |  | $ 103.16 |  |  |  |  | $ 103.16 |  |  |  | $ 103.16 |  |
Gross proceeds from issuance of common stock |  |  |  |  | $ 163,200,000 |  |  |  |  |  |  |  |  |  |  |
Jeffries LLC Sales Agreement | At-The-Market | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Shares issued and sold |  |  |  | 1,146,724 |  |  |  |  |  |  |  |  |  |  |  |
Gross proceeds from issuance of common stock |  |  |  | $ 136,800,000 |  |  |  |  |  |  |  |  |  |  |  |
Net proceeds from sale of common stock |  |  |  |  |  |  |  |  |  |  |  |  | $ 290,500,000 |  |  |
Jeffries LLC Sales Agreement | Maximum | At-The-Market |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Commission rate |  |  |  |  |  | 3.00% |  |  |  |  |  |  |  |  |  |
Aggregate gross proceeds of shares authorized under ATM sales agreement |  |  |  |  |  | $ 300,000,000.0 |  |  |  |  |  |  |  |  |  |
Guide Therapeutics, Inc. | Merger Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business combination upfront consideration paid in common stock | $ 120,000,000.0 |  |  |  |  |  | $ 120,000,000.0 |  |  |  |  |  |  |  |  |
Merger agreement description |  |  |  |  |  |  |  |  |  |  |  |  |  | the Company paid Guide’s former stockholders and optionholders upfront consideration in an aggregate amount of $120.0 million, excluding customary purchase price adjustments, in shares of its common stock, based upon the volume-weighted average price of the Company’s common stock over the ten-trading day period ending on February 19, 2021. |  |
Milestone payment method, description |  |  |  |  |  |  |  |  |  |  |  |  |  | In addition, Guide’s former stockholders and optionholders are eligible to receive up to an additional $100.0 million in technology milestone payments and $220.0 million in product milestone payments, payable in the Company’s common stock. |  |
Guide Therapeutics, Inc. | Technology Milestones | Merger Agreement | Former Stockholders and Optionholders | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Potential milestone payable in form of common stock | 100,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Guide Therapeutics, Inc. | Product Milestones | Merger Agreement | Former Stockholders and Optionholders | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Potential milestone payable in form of common stock | $ 220,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

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