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Stock Option and Grant Plan (Tables)
 6 Months Ended
Jun. 30, 2021
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]  
Summary of Stock-based Compensation Expense

Stock-based compensation expense recorded as research and development and general and administrative expenses in the condensed consolidated statements of operations and other comprehensive loss is as follows (in thousands):

 

 

Three Months Ended
June 30,

 

 

Six Months Ended
June 30,

 

 

 

2021

 

 

2020

 

 

2021

 

 

2020

 

Research and development

 

$

6,340

 

 

$

1,805

 

 

$

9,495

 

 

$

3,578

 

General and administrative

 

 

4,112

 

 

 

964

 

 

 

5,605

 

 

 

1,983

 

Total stock-based compensation expense

 

$

10,452

 

 

$

2,769

 

 

$

15,100

 

 

$

5,561

 
Summary of Option Activity Under Equity Award Plans summary of option activity under the Company’s equity award plans:

 

 

Number
of options

 

 

Weighted
average
exercise
price

 

Outstanding at December 31, 2020

 

 

5,336,441

 

 

$

9.70

 

Granted

 

 

1,236,543

 

 

 

86.38

 

Exercised

 

 

(605,509

)

 

 

9.65

 

Forfeitures

 

 

(32,731

)

 

 

28.84

 

Outstanding at June 30, 2021

 

 

5,934,744

 

 

 

25.58

 

Exercisable as of June 30, 2021

 

 

1,733,868

 

 

$

7.48

 
Summary of Restricted Stock Activity

The following table summarizes the Company’s restricted stock activity:

 

 

Shares

 

 

Weighted-
average grant
date fair
value

 

Unvested as of December 31, 2020

 

 

1,275,338

 

 

$

10.95

 

Issued

 

 

619,030

 

 

 

88.49

 

Vested

 

 

(599,207

)

 

 

4.44

 

Cancelled

 

 

(4,500

)

 

 

80.04

 

Unvested as of June 30, 2021

 

 

1,290,661

 

 

$

51.04