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Nature of the Business and Basis of Presentation - Additional Information (Details) - USD ($)
1 Months Ended 3 Months Ended 4 Months Ended 6 Months Ended
Feb. 23, 2021
Jan. 16, 2021
Aug. 03, 2021
Jul. 31, 2021
Jun. 30, 2021
Apr. 30, 2021
Feb. 28, 2021
Oct. 31, 2020
Feb. 29, 2020
Jun. 30, 2021
Mar. 31, 2021
Mar. 31, 2020
Jul. 31, 2021
Jun. 30, 2021
Jul. 07, 2021
Dec. 31, 2020
Nature Of Business And Basis Of Presentation [Line Items]                                
Gross proceeds from issuance of common stock               $ 135,100,000                
Accumulated deficit         $ 675,449,000         $ 675,449,000       $ 675,449,000   $ 397,636,000
Cash, cash equivalents, and marketable securities         $ 615,300,000         $ 615,300,000       $ 615,300,000    
Common Stock                                
Nature Of Business And Basis Of Presentation [Line Items]                                
Shares issued and sold               5,750,000   1,761,285 2,795,700 12,176,471        
Public offering price per share               $ 23.50                
Net proceeds from sale of common stock               $ 126,600,000 $ 188,300,000              
IPO | Common Stock                                
Nature Of Business And Basis Of Presentation [Line Items]                                
Shares issued and sold                 12,176,471              
Public offering price per share                 $ 17.00              
Gross proceeds from issuance of common stock                 $ 207,000,000.0              
Net proceeds from sale of common stock                 $ 188,300,000              
Shares issued upon conversion of preferred stock                 29,127,523              
Underwriters Option | Common Stock                                
Nature Of Business And Basis Of Presentation [Line Items]                                
Shares issued and sold               750,000 1,588,235              
Private Placement                                
Nature Of Business And Basis Of Presentation [Line Items]                                
Gross proceeds from issuance of common stock   $ 260,000,000.0                            
Private Placement | Common Stock                                
Nature Of Business And Basis Of Presentation [Line Items]                                
Shares issued and sold   2,795,700                            
Public offering price per share   $ 93.00                            
Net proceeds from sale of common stock   $ 252,000,000.0                            
Jeffries LLC Amended Sales Agreement | Subsequent Event                                
Nature Of Business And Basis Of Presentation [Line Items]                                
Gross proceeds from issuance of common stock     $ 11,000,000.0                          
Jeffries LLC Amended Sales Agreement | Common Stock | Subsequent Event                                
Nature Of Business And Basis Of Presentation [Line Items]                                
Shares issued and sold     108,617                          
Jeffries LLC Amended Sales Agreement | At-The-Market | Subsequent Event                                
Nature Of Business And Basis Of Presentation [Line Items]                                
Shares issued and sold     108,617                          
Aggregate gross proceeds of shares authorized under ATM sales agreement                             $ 500,000,000.0  
Gross proceeds from issuance of common stock     $ 11,000,000.0                          
Jeffries LLC Sales Agreement | At-The-Market                                
Nature Of Business And Basis Of Presentation [Line Items]                                
Stock sold during period shares, new issues                           2,908,009    
Gross proceeds from sale of common stock                           $ 300,000,000.0    
Shares issued and sold         1,761,285                      
Public offering price per share         $ 103.16         $ 103.16       $ 103.16    
Gross proceeds from issuance of common stock         $ 163,200,000                      
Jeffries LLC Sales Agreement | At-The-Market | Subsequent Event                                
Nature Of Business And Basis Of Presentation [Line Items]                                
Shares issued and sold       1,146,724                        
Gross proceeds from issuance of common stock       $ 136,800,000                        
Net proceeds from sale of common stock                         $ 290,500,000      
Jeffries LLC Sales Agreement | Maximum | At-The-Market                                
Nature Of Business And Basis Of Presentation [Line Items]                                
Commission rate           3.00%                    
Aggregate gross proceeds of shares authorized under ATM sales agreement           $ 300,000,000.0                    
Guide Therapeutics, Inc. | Merger Agreement                                
Nature Of Business And Basis Of Presentation [Line Items]                                
Business combination upfront consideration paid in common stock $ 120,000,000.0           $ 120,000,000.0                  
Merger agreement description                           the Company paid Guide’s former stockholders and optionholders upfront consideration in an aggregate amount of $120.0 million, excluding customary purchase price adjustments, in shares of its common stock, based upon the volume-weighted average price of the Company’s common stock over the ten-trading day period ending on February 19, 2021.    
Milestone payment method, description                           In addition, Guide’s former stockholders and optionholders are eligible to receive up to an additional $100.0 million in technology milestone payments and $220.0 million in product milestone payments, payable in the Company’s common stock.    
Guide Therapeutics, Inc. | Technology Milestones | Merger Agreement | Former Stockholders and Optionholders | Maximum                                
Nature Of Business And Basis Of Presentation [Line Items]                                
Potential milestone payable in form of common stock 100,000,000.0                              
Guide Therapeutics, Inc. | Product Milestones | Merger Agreement | Former Stockholders and Optionholders | Maximum                                
Nature Of Business And Basis Of Presentation [Line Items]                                
Potential milestone payable in form of common stock $ 220,000,000.0