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Leases - Additional Information (Details)
$ in Thousands
 1 Months Ended 3 Months Ended 6 Months Ended
Aug. 31, 2020
USD ($)
ft²
Option
Apr. 30, 2020
USD ($)
Option
Mar. 31, 2020
USD ($)
Jul. 31, 2019
Jun. 30, 2019
Apr. 30, 2019
USD ($)
Option
Oct. 31, 2018
Feb. 28, 2018
USD ($)
ft²
Jun. 30, 2021
USD ($)
Jun. 30, 2021
USD ($)
Jun. 30, 2020
USD ($)
Jan. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Oct. 31, 2020
USD ($)
Lessee Lease Description [Line Items]                            
Operating lease, option to extend                   option to extend the lease for two terms of five years each, which are not reasonably certain of exercise.        
Operating lease right-of-use assets                 $ 105,315 $ 105,315     $ 86,859  
Lease liability                 $ 136,284 136,284        
Increase in operating lease liability                   $ 11,888 $ (1,801)      
Office and Laboratory Space                            
Lessee Lease Description [Line Items]                            
Square feet of office and laboratory space | ft²               38,203            
Operating lease, commencement month and year       2019-10 2019-10     2018-03            
Operating lease, termination month and year       2021-12 2021-12     2028-09            
Operating lease, existence of option to extend           true                
Operating lease, number of renewal options | Option           2                
Operating lease, option to extend term           5 years                
Leasehold improvements landlord allowance           $ 23,400   $ 6,100            
Operating lease, termination date                 Feb. 28, 2034          
Increase in operating lease right-of-use assets                 $ 500          
Increase in operating lease liability                 $ 500          
Operating lease term                 12 years 12 years        
Office and Laboratory Space | Letter of Credit                            
Lessee Lease Description [Line Items]                            
Lessee, operating lease, security deposit           $ 11,800                
Office and Laboratory Space | First Phase of Lease in October 2020                            
Lessee Lease Description [Line Items]                            
Operating lease, commencement month and year           2020-10                
Operating lease right-of-use assets                           $ 66,800
Lease liability                           $ 68,800
Office and Laboratory Space | Second Phase of Lease in January 2021                            
Lessee Lease Description [Line Items]                            
Operating lease, commencement month and year           2021-01                
Operating lease right-of-use assets                       $ 22,000    
Lease liability                       $ 23,000    
Laboratory Space                            
Lessee Lease Description [Line Items]                            
Operating lease, commencement month and year   2020-04         2019-04              
Operating lease, termination month and year   2025-12                        
Operating lease, amendment month and year   2020-04 2020-03                      
Operating lease, option to extend   The amended lease is subject to fixed-rate rent escalations and provides an option to extend the lease for two additional two-year periods through December 31, 2029, which are not reasonably certain of being exercised.                        
Operating lease, existence of option to extend   true                        
Operating lease, number of renewal options | Option   2                        
Operating lease, option to extend term   2 years                        
Operating lease right-of-use assets   $ 1,800 $ 4,200                      
Lease liability   $ 1,800 $ 4,200                      
Manufacturing Facility | Alexandria Real Estate Equities, Inc.                            
Lessee Lease Description [Line Items]                            
Operating lease, existence of option to extend true                          
Operating lease, number of renewal options | Option 2                          
Operating lease, option to extend term 5 years                          
Manufacturing facility, number of square feet | ft² 100,000                          
Operating lease term 15 years                          
Lessee operating lease, description                   The lease has a term of 15 years following the commencement date and provides the Company the option to extend the lease term for two five-year terms. It is subject to fixed rate escalation increases and also provides up to $20.0 million for reimbursement of tenant improvements. As the lease had not commenced as of June 30, 2021, the Company has not recorded an operating lease ROU asset or lease liability for this lease in the accompanying condensed consolidated balance sheets.        
Lessee, operating lease, lease not yet commenced anticipated undiscounted lease payments due $ 63,900                          
Anticipated period for leasehold improvements 5 years                          
Manufacturing Facility | Alexandria Real Estate Equities, Inc. | Maximum                            
Lessee Lease Description [Line Items]                            
Leasehold improvements landlord allowance $ 20,000                          
Anticipated leasehold improvement amount $ 83,000