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Guide Acquisition - Additional Information (Details) - USD ($) $ in Thousands		1 Months Ended	3 Months Ended			6 Months Ended
	Feb. 23, 2021	Feb. 28, 2021	Jun. 30, 2021	Mar. 31, 2021	Mar. 31, 2020	Jun. 30, 2021	Dec. 31, 2020
Business Acquisition [Line Items]
Value of shares issued for upfront payment of acquisition				$ 120,032
Research and development expense						$ 154,953
Issuance of common stock from initial public offering/private placement/At-the-Market offering, net of issuance costs			$ 157,785	252,005	$ 188,323
Business combination liability for milestones at fair value			37,559			37,559	$ 0
Common Stock
Business Acquisition [Line Items]
Value of shares issued for upfront payment of acquisition				10
Issuance of common stock from initial public offering/private placement/At-the-Market offering, net of issuance costs			18	$ 28	$ 122
Guide Therapeutics, Inc. | Merger Agreement
Business Acquisition [Line Items]
Business Acquisition, merger agreement date	Feb. 23, 2021
Business combination upfront consideration paid in common stock	$ 120,000	$ 120,000
Value of shares issued for upfront payment of acquisition	120,000
Research and development expense	155,000
Business combination liability for milestones at fair value	$ 36,500		$ 37,600			$ 37,600
Guide Therapeutics, Inc. | Merger Agreement | Common Stock
Business Acquisition [Line Items]
Number of shares issued for upfront payment of acquisition.	1,087,153
Guide Therapeutics, Inc. | Merger Agreement | Technology Milestones | Maximum | Former Stockholders and Optionholders
Business Acquisition [Line Items]
Potential milestone payable in form of common stock	$ 100,000
Guide Therapeutics, Inc. | Merger Agreement | Product Milestones | Maximum | Former Stockholders and Optionholders
Business Acquisition [Line Items]
Potential milestone payable in form of common stock	$ 220,000

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Amount of liability recognized arising from contingent consideration in a business combination, expected to be settled beyond one year or the normal operating cycle, if longer.

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