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License Agreements - Harvard License Agreement - Change in Fair Value of Success Payment Liability (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]        
Change in fair value of derivative liabilities $ 42,300 $ 8,700 $ 44,200 $ 11,400
Harvard        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]        
Change in fair value of derivative liabilities $ 21,100 $ 4,400 $ 22,100 $ 5,700