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Preferred and Common Stock - Additional Information (Details) - USD ($)
1 Months Ended 3 Months Ended 4 Months Ended 6 Months Ended
Jan. 16, 2021
Aug. 03, 2021
Jul. 31, 2021
Jun. 30, 2021
Apr. 30, 2021
Oct. 31, 2020
Feb. 29, 2020
Jun. 30, 2021
Mar. 31, 2021
Mar. 31, 2020
Jul. 31, 2021
Jun. 30, 2021
Jul. 07, 2021
May 10, 2021
Dec. 31, 2020
Jan. 31, 2020
Class Of Stock [Line Items]                                
Preferred stock, shares authorized       25,000,000       25,000,000       25,000,000     25,000,000 25,000,000
Preferred stock, par value per share       $ 0.01       $ 0.01       $ 0.01     $ 0.01 $ 0.01
Common stock, shares authorized       250,000,000       250,000,000       250,000,000     250,000,000 250,000,000
Common stock, par or stated value per share       $ 0.01       $ 0.01       $ 0.01     $ 0.01 $ 0.01
Gross proceeds from issuance of common stock           $ 135,100,000                    
Common stock, voting rights                       The holders of the Company’s common stock are entitled to one vote for each share of common stock.        
Common Stock                                
Class Of Stock [Line Items]                                
Shares issued and sold           5,750,000   1,761,285 2,795,700 12,176,471            
Public offering price per share           $ 23.50                    
Net proceeds from sale of common stock           $ 126,600,000 $ 188,300,000                  
Issuance of common stock for success payment liability, Shares               349,650                
Prime Medicine Inc | Common Stock                                
Class Of Stock [Line Items]                                
Shares issued and sold           200,307                    
Broad Institute                                
Class Of Stock [Line Items]                                
Issuance of common stock for success payment liability, Shares       174,825                        
Success payments liability                           $ 15,000,000.0    
Harvard Institute                                
Class Of Stock [Line Items]                                
Issuance of common stock for success payment liability, Shares       174,825                        
Success payments liability                           $ 15,000,000.0    
Jeffries LLC Amended Sales Agreement | Subsequent Event                                
Class Of Stock [Line Items]                                
Gross proceeds from issuance of common stock   $ 11,000,000.0                            
Jeffries LLC Amended Sales Agreement | Common Stock | Subsequent Event                                
Class Of Stock [Line Items]                                
Shares issued and sold   108,617                            
IPO | Common Stock                                
Class Of Stock [Line Items]                                
Shares issued and sold             12,176,471                  
Public offering price per share             $ 17.00                  
Gross proceeds from issuance of common stock             $ 207,000,000.0                  
Net proceeds from sale of common stock             $ 188,300,000                  
Shares issued upon conversion of preferred stock             29,127,523                  
Underwriters Option | Common Stock                                
Class Of Stock [Line Items]                                
Shares issued and sold           750,000 1,588,235                  
Private Placement                                
Class Of Stock [Line Items]                                
Gross proceeds from issuance of common stock $ 260,000,000.0                              
Private Placement | Common Stock                                
Class Of Stock [Line Items]                                
Shares issued and sold 2,795,700                              
Public offering price per share $ 93.00                              
Net proceeds from sale of common stock $ 252,000,000.0                              
At-The-Market | Jeffries LLC Amended Sales Agreement | Subsequent Event                                
Class Of Stock [Line Items]                                
Shares issued and sold   108,617                            
Gross proceeds from issuance of common stock   $ 11,000,000.0                            
Aggregate gross proceeds of shares authorized under ATM sales agreement                         $ 500,000,000.0      
At-The-Market | Jeffries LLC Sales Agreement                                
Class Of Stock [Line Items]                                
Gross proceeds from sale of common stock                       $ 300,000,000.0        
Stock sold during period shares, new issues                       2,908,009        
Shares issued and sold       1,761,285                        
Public offering price per share       $ 103.16       $ 103.16       $ 103.16        
Gross proceeds from issuance of common stock       $ 163,200,000                        
At-The-Market | Jeffries LLC Sales Agreement | Maximum                                
Class Of Stock [Line Items]                                
Aggregate gross proceeds of shares authorized under ATM sales agreement         $ 300,000,000.0                      
Commission rate         3.00%                      
At-The-Market | Jeffries LLC Sales Agreement | Subsequent Event                                
Class Of Stock [Line Items]                                
Shares issued and sold     1,146,724                          
Gross proceeds from issuance of common stock     $ 136,800,000                          
Net proceeds from sale of common stock                     $ 290,500,000