Net Loss per Share

9 Months Ended

Sep. 30, 2022

14. Net loss per share

For periods in which the Company reports a net loss, potentially dilutive securities have been excluded from the computation of diluted net loss per share as their effects would be anti-dilutive. Therefore, the weighted average number of common shares outstanding used to calculate both basic and diluted net loss per share is the same. The Company excluded the following potential common shares, presented based on amounts outstanding at period end, from the computation of diluted net loss per share because including them would have had an anti-dilutive effect:


	As of September 30,
	2022		2021
Unvested restricted stock		1,647,779		1,286,834
Outstanding options to purchase common stock		7,607,063		6,139,250
Total		9,254,842		7,426,084

The following table summarizes the computation of basic and diluted net loss per share of the Company (in thousands, except share and per share amounts):


	Three Months Ended September 30,						Nine Months Ended September 30,
	2022			2021			2022			2021
Numerator:
Net loss	$	(109,575	)	$	(28,118	)	$	(250,739	)	$	(305,931	)
Denominator:
Weighted average common shares outstanding, basic and diluted		70,343,196			66,377,611			69,758,434			62,960,219
Net loss per common share, basic and diluted	$	(1.56	)	$	(0.42	)	$	(3.59	)	$	(4.86	)