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Leases - Additional Information (Details)
$ in Thousands
 1 Months Ended 3 Months Ended 9 Months Ended
Jun. 30, 2022
USD ($)
Aug. 31, 2020
USD ($)
ft²
Option
Apr. 30, 2019
USD ($)
Option
Oct. 31, 2018
Option
Feb. 28, 2018
USD ($)
ft²
Jun. 30, 2021
USD ($)
Sep. 30, 2022
USD ($)
Mar. 31, 2023
Dec. 31, 2021
USD ($)
Aug. 31, 2021
USD ($)
Jan. 31, 2021
USD ($)
Oct. 31, 2020
USD ($)
Lessee Lease Description [Line Items]                        
Operating lease right-of-use assets             $ 115,534   $ 102,718      
Lease liability             174,898          
Office and Laboratory Space                        
Lessee Lease Description [Line Items]                        
Square feet of office and laboratory space | ft²         38,203              
Operating lease, commencement month and year         2018-03              
Operating lease, termination month and year         2028-09 2034-02            
Operating lease, option to extend     option to extend the lease for two terms of five years each, which are not reasonably certain of exercise.   a term extension option, which is not reasonably certain of exercise.              
Operating lease, existence of option to extend     true   true              
Operating lease, number of renewal options | Option     2                  
Operating lease, option to extend term     5 years                  
Leasehold improvements landlord allowance     $ 23,400   $ 6,100              
Increase in operating lease right-of-use assets           $ 500            
Increase in operating lease liability           $ 500            
Operating lease term           12 years            
Lessee, operating lease, lease not yet commenced anticipated undiscounted lease payments due                   $ 11,100    
Office and Laboratory Space | Letter of Credit                        
Lessee Lease Description [Line Items]                        
Lessee, operating lease, security deposit             9,700   9,700      
Office and Laboratory Space | First Phase of Lease in October 2020                        
Lessee Lease Description [Line Items]                        
Operating lease, commencement month and year     2020-10                  
Rent payments beginning month and year     2021-08                  
Operating lease right-of-use assets                       $ 66,800
Lease liability                       $ 68,800
Office and Laboratory Space | Second Phase of Lease in January 2021                        
Lessee Lease Description [Line Items]                        
Operating lease, commencement month and year     2021-01                  
Rent payments beginning month and year     2022-02                  
Operating lease right-of-use assets                     $ 22,000  
Lease liability                     $ 23,000  
Laboratory Space                        
Lessee Lease Description [Line Items]                        
Operating lease, commencement month and year       2019-04                
Operating lease, termination month and year       2025-12                
Operating lease, option to extend       The amended lease is subject to fixed-rate rent escalations and provides an option to extend the lease for two additional two-year periods through December 31, 2029, which are not reasonably certain of being exercised.                
Operating lease, existence of option to extend       true                
Operating lease, number of renewal options | Option       2                
Operating lease, option to extend term       2 years                
Operating lease right-of-use assets             14,100          
Lease liability             $ 14,000          
Manufacturing Facility                        
Lessee Lease Description [Line Items]                        
Operating lease, commencement month and year   2022-06                    
Operating lease, existence of option to extend   true                    
Operating lease, number of renewal options | Option   2                    
Operating lease, option to extend term   5 years                    
Operating lease right-of-use assets $ 13,600                      
Lease liability 30,400                      
Tenant improvement allowance $ 16,800                      
Leasehold improvements landlord allowance   $ 20,000                    
Manufacturing facility, number of square feet | ft²   100,000                    
Lessee operating lease, description             The lease will terminate 15 years from the rent commencement date. The lease is subject to fixed-rate rent escalations and provides for $20.0 million in tenant improvements and the option to extend the lease for two terms of five years each, which were not reasonably certain of exercise as of September 30, 2022. The Company determined that it is the accounting owner of all tenant improvements under the lease. Upon executing the lease in August 2020, the Company made a security deposit of $1.5 million in the form of a letter of credit, which is included in restricted cash as of September 30, 2022 and December 31, 2021. Upon commencement of this lease in June 2022, the Company recorded an operating lease ROU asset of $13.6 million and a lease liability of $30.4 million. The variance between the ROU asset and lease liability recorded relates to $16.8 million of tenant improvement allowance completed through the lease commencement date. The $16.8 million of tenant improvement allowance is presented as an operating cash inflow and investing cash outflow within the Company’s condensed consolidated statements of cash flows. The rent payments are subject to adjustment following the determination of the total project costs of the landlord and represent in substance fixed payments that are included in the total future minimum lease payments.          
Manufacturing Facility | Letter of Credit                        
Lessee Lease Description [Line Items]                        
Lessee, operating lease, security deposit             $ 1,500   $ 1,500      
Manufacturing Facility | Scenario Forecast                        
Lessee Lease Description [Line Items]                        
Operating lease term               15 years